FCER2 Protein (AA 48-321) (His tag)
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- 抗原 See all FCER2 蛋白
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 48-321
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FCER2 protein is labelled with His tag.
- 品牌
- MABSol®
- 序列
- AA 48-321
- 产品特性
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 32.6 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product FCER2 蛋白
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Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)
FCER2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) protein (GST tag)FCER2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)FCER2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (Fc Tag)FCER2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-331) protein (Strep Tag)Crystallography grade FCER2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) protein (Strep Tag)Crystallography grade FCER2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) protein (His tag)Crystallography grade FCER2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 50-331) protein (His tag)Crystallography grade FCER2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-321) protein (rho-1D4 tag)Crystallography grade FCER2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) (Active) protein (His tag,AVI tag,Biotin)FCER2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 150 mM NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: 4-8°C for 1 year in lyophilized state 4-8°C for 1 month under sterile conditions after reconstitution -20°C to -70°C for 3 months under sterile conditions after reconstitution
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- 抗原
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 别名
- CD23 (FCER2 产品)
- 别名
- BLAST-2 Protein, CD23 Protein, CD23A Protein, CLEC4J Protein, FCE2 Protein, IGEBF Protein, Fcer2a Protein, Fc fragment of IgE receptor II Protein, FCER2 Protein, Fcer2 Protein
- 背景
- Cluster of differentiation 23 (CD23) is also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. CD23 is known to have role of transportation in antibody feedback regulation. Antigen that enters the blood stream is captured by antigen specific IgE antibodies. The IgE immune complexes that are formed bind to CD23 Molecules on B cells, and are transported to the B cell follicles of the spleen. The antigen is then transferred from CD23+ B cells to CD11c+ antigen presenting cells. The CD11c+ cells in turn present the antigen to CD4+ T cells, which can lead to an enhanced antibody response. In flow cytometry, CD23 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell leukemia (CD23-negative).
- 分子量
- 32.9 kDa
- NCBI登录号
- NP_001993
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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