FCER2 Protein (Fc Tag)
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- 抗原 See all FCER2 蛋白
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This FCER2 protein is labelled with Fc Tag.
- 原理
- Recombinant Rat CD23 Protein (Fc Tag)
- 序列
- Glu50-Pro331
- 产品特性
- A DNA sequence encoding the rat FCER2 (Q6AZ45) (Glu50-Pro331) was expressed with Fc region of human IgG1 at the N-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product FCER2 蛋白
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Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)
FCER2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) protein (GST tag)FCER2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) protein (His tag)FCER2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-331) protein (Strep Tag)Crystallography grade FCER2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 1-321) protein (Strep Tag)Crystallography grade FCER2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) protein (His tag)Crystallography grade FCER2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 50-331) protein (His tag)Crystallography grade FCER2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 150-321) protein (rho-1D4 tag)Crystallography grade FCER2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2) (AA 48-321) (Active) protein (His tag,AVI tag,Biotin)FCER2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, PH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
- 别名
- CD23 (FCER2 产品)
- 别名
- BLAST-2 Protein, CD23 Protein, CD23A Protein, CLEC4J Protein, FCE2 Protein, IGEBF Protein, Fcer2a Protein, Fc fragment of IgE receptor II Protein, FCER2 Protein, Fcer2 Protein
- 背景
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Background: Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).
Synonym: FCER2,Fcer2a
- 分子量
- 60.2 kDa
- UniProt
- Q6AZ45
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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