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Annexin V Protein (AA 1-320) (His tag)

ANXA5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >98 % as determined by SDS-PAGE.
产品编号 ABIN2180594
发货至: 中国
  • 抗原 See all Annexin V (ANXA5) 蛋白
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    蛋白类型
    Recombinant
    产品特性
    AA 1-320
    宿主
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 24
    • 8
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Annexin V protein is labelled with His tag.
    序列
    AA 1-320
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.8 kDa. The protein migrates as 36.8 kDa under reducing (R) condition (SDS-PAGE).
    纯度
    >98 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ANXA5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • 抗原
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    别名
    Annexin A5 (ANXA5 产品)
    别名
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    背景
    Annexin A5 is a phospholipid binding protein, which binds with high affinity and selectivity to PS in the presence of calcium. PS is predominantly located in membrane leaflets, which face the cytosol. However, recent findings show that each cell type has the molecular machinery to expose PS at its cell surface. This machinery is activated during the execution of apoptosis. Once PS is exposed at the cell surface it exhibits procoagulant and proinflammatory activities. Annexin A5 will bind to the PS-exposing apoptotic cell and can inhibit the procoagulant and proinflammatory activities of the dying cell. Annexin A5 has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin A5 is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).
    分子量
    36.8 kDa
    途径
    Apoptosis
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