Peroxiredoxin 1 Protein (PRDX1) (AA 1-199) (His tag)
-
- 抗原 See all Peroxiredoxin 1 (PRDX1) 蛋白
- Peroxiredoxin 1 (PRDX1)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-199
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This Peroxiredoxin 1 protein is labelled with His tag.
- 原理
- Recombinant Human Peroxiredoxin-1/PRDX1 (N, C-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQKL EHHHHHH
- 产品特性
- Recombinant Human Peroxiredoxin-1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys199) of Human peroxiredoxin 1 fused with a 6His tag at the N-terminus and C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PRDX1 蛋白
-
Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)
PRDX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)PRDX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Peroxiredoxin 1 (PRDX1) protein (His tag)PRDX1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % as determined by SDS-PAGE
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, 0.1 mM DTT, pH 6.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
-
- 抗原
- Peroxiredoxin 1 (PRDX1)
- 别名
- Peroxiredoxin-1 (PRDX1 产品)
- 别名
- MSP23 Protein, NKEF-A Protein, NKEFA Protein, PAG Protein, PAGA Protein, PAGB Protein, PRX1 Protein, PRXI Protein, TDPX2 Protein, NkefA Protein, OSF-3 Protein, OSF3 Protein, Paga Protein, PrdxI Protein, PrxI Protein, TDX2 Protein, TPxA Protein, Tdpx2 Protein, prx1 Protein, Hbp23 Protein, MGC80194 Protein, MGC84820 Protein, PRDX1 Protein, msp23 Protein, nkefa Protein, pag Protein, paga Protein, pagb Protein, prx-1 Protein, prxi Protein, tdpx2 Protein, hm:zehl0637 Protein, zgc:110343 Protein, TPX-2 Protein, peroxiredoxin 1 Protein, peroxiredoxin 1 S homeolog Protein, peroxiredoxin-1 pseudogene Protein, PRDX1 Protein, Prdx1 Protein, prdx1.S Protein, prdx1 Protein, LOC100350232 Protein
- 背景
-
Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.
Synonyms: Peroxiredoxin-1,Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,PAGA, PAGB, TDPX2 - 分子量
- 25.3 kDa
- UniProt
- Q06830
- 途径
- p53 Pathway, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
-
