HYAL1 Protein (AA 22-435) (His tag)
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- 抗原 See all HYAL1 蛋白
- HYAL1 (Hyaluronidase-1 (HYAL1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-435
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宿主
- 人
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资源
- 人细胞
- 标记
- This HYAL1 protein is labelled with His tag.
- 原理
- Recombinant Human Hyaluronidase-1/HYAL1 (C-6His)
- 序列
- FRGPLLPNRP FTTVWNANTQ WCLERHGVDV DVSVFDVVAN PGQTFRGPDM TIFYSSQLGT YPYYTPTGEP VFGGLPQNAS LIAHLARTFQ DILAAIPAPD FSGLAVIDWE AWRPRWAFNW DTKDIYRQRS RALVQAQHPD WPAPQVEAVA QDQFQGAARA WMAGTLQLGR ALRPRGLWGF YGFPDCYNYD FLSPNYTGQC PSGIRAQNDQ LGWLWGQSRA LYPSIYMPAV LEGTGKSQMY VQHRVAEAFR VAVAAGDPNL PVLPYVQIFY DTTNHFLPLD ELEHSLGESA AQGAAGVVLW VSWENTRTKE SCQAIKEYMD TTLGPFILNV TSGALLCSQA LCSGHGRCVR RTSHPKALLL LNPASFSIQL TPGGGPLSLR GALSLEDQAQ MAVEFKCRCY PGWQAPWCER KSMWVDHHHH HH
- 产品特性
- Recombinant Human Hyaluronidase-1/HYAL1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe22-Trp435) of Human HYAL1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Discover our top product HYAL1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- HYAL1 (Hyaluronidase-1 (HYAL1))
- 别名
- Hyaluronidase-1/HYAL1 (HYAL1 产品)
- 别名
- HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
- 背景
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Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Synonyms: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1 - 分子量
- 47.18 kDa
- UniProt
- Q12794
- 途径
- Glycosaminoglycan Metabolic Process
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