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HYAL1 Protein (His tag)

HYAL1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318588
发货至: 中国
  • 抗原 See all HYAL1 蛋白
    HYAL1 (Hyaluronidase-1 (HYAL1))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 3
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人细胞
    标记
    This HYAL1 protein is labelled with His tag.
    原理
    Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)
    序列
    Phe22-Trp435
    产品特性
    Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HYAL1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    HYAL1 (Hyaluronidase-1 (HYAL1))
    别名
    Hyaluronidase-1/HYAL1 (HYAL1 产品)
    别名
    HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
    背景

    Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

    Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1

    分子量
    47.2 kDa
    UniProt
    Q12794
    途径
    Glycosaminoglycan Metabolic Process
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