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VEGFD Protein (AA 93-201) (His tag)

Figf 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN2115424
发货至: 中国
  • 抗原 See all VEGFD (Figf) 蛋白
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    蛋白类型
    Recombinant
    产品特性
    AA 93-201
    宿主
    • 9
    • 3
    • 3
    • 2
    资源
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This VEGFD protein is labelled with His tag.
    原理
    Recombinant Human VEGF-D/FIGF (C-6His)
    序列
    FYDIETLKVI DEEWQRTQCS PRETCVEVAS ELGKSTNTFF KPPCVNVFRC GGCCNEESLI CMNTSTSYIS KQLFEISVPL TSVPELVPVK VANHTGCKCL PTAPRHPYSH HHHHH
    产品特性
    Recombinant Human Vascular Endothelial Growth Factor D/VEGFD produced by our mammalian expression system in human cells is expressed with sequence (Phe93-Ser201) of Human VEGFD.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product Figf 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    别名
    VEGFD-FIGF (Figf 产品)
    别名
    FIGF Protein, vegfd Protein, vegf-d Protein, VEGFD Protein, AI325264 Protein, VEGF-D Protein, Vegfd Protein, Vegf-d Protein, vascular endothelial growth factor D Protein, Vascular endothelial growth factor D Protein, VEGFD Protein, vegfd Protein, vegfd.L Protein, Vegfd Protein
    背景
    Vascular endothelial growth factor D (VEGF-D), also known as c-fos-induced growth factor (FIGF), is a secreted glycoprotein of the VEGF/PDGF family. VEGFs regulate angiogenesis and lymphangiogenesis during development and tumor growth, and are characterized by eight conserved cysteine residues that form a cystine knot structure.Mouse and human VEGF-D are ligands for VEGF Receptor 3 (VEGF R3, also called Flt4) that are active across species and show enhanced affinity when processed . Processed human VEGF-D is also a ligand for VEGF R2, also called Flk1 or KDR. VEGF R3 is strongly expressed in lymphatic endothelial cells and is essential for regulation of the growth and differentiation of lymphatic endothelium. While VEGF-C is the critical ligand for VEGF R3 during embryonic lymphatic development, VEGF-D is most active in neonatal lymphatic maturation and bone growth. Both promote tumor lymphangiogenesis. Consonant with their activity on VEGF receptors, binding of VEGF-C and VEGF-D.
    Synonyms: Vascular Endothelial Growth Factor D, VEGF-D, c-Fos-Induced Growth Factor, FIGF, VEGFD
    分子量
    12.18 kDa
    UniProt
    O43915
    途径
    RTK signaling
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