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M-CSF/CSF1 Protein (AA 33-254)

CSF1 宿主: 大鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN2115423
发货至: 中国
  • 抗原 See all M-CSF/CSF1 (CSF1) 蛋白
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    蛋白类型
    Recombinant
    产品特性
    AA 33-254
    宿主
    • 31
    • 18
    • 5
    • 1
    大鼠
    资源
    • 20
    • 19
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人细胞
    原理
    Recombinant Rat M-CSF/CSF1
    序列
    EVSEHCSHMI GNGHLQILQQ LIDSQMETAC LIEYKFVDQE QLDDPVCYLK KAFVLVQVII EETMRFKDNT PNANATERLQ ELSMKLNSCF IKDYKEQNEA CVQTYKESPL RLLEKIKNFF NETKNFLEKD WNIFSKNCND SFAKCSSRDV VTKPDCNCLY PKATPSSDLA SASPHQPPAP SMAPLADLAW DDSQRTEGSS LLPSDLPLRI EDPGSAKQRP PR
    产品特性
    Recombinant Rat Macrophage colony-stimulating factor 1/MCSF/Csf1 produced by transfected human cells is a secreted protein with sequence (Gln33-Arg254) of Rat MCSF.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CSF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    别名
    MCSF (CSF1 产品)
    背景
    Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
    Synonyms: Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1
    分子量
    25.2 kDa
    UniProt
    Q8JZQ0
    途径
    RTK signaling
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