M-CSF/CSF1 Protein (AA 33-254)
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Quick Overview for M-CSF/CSF1 Protein (AA 33-254) (ABIN2115423)
抗原
See all M-CSF/CSF1 (CSF1) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 33-254
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原理
- Recombinant Rat M-CSF/CSF1
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序列
- EVSEHCSHMI GNGHLQILQQ LIDSQMETAC LIEYKFVDQE QLDDPVCYLK KAFVLVQVII EETMRFKDNT PNANATERLQ ELSMKLNSCF IKDYKEQNEA CVQTYKESPL RLLEKIKNFF NETKNFLEKD WNIFSKNCND SFAKCSSRDV VTKPDCNCLY PKATPSSDLA SASPHQPPAP SMAPLADLAW DDSQRTEGSS LLPSDLPLRI EDPGSAKQRP PR
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产品特性
- Recombinant Rat Macrophage colony-stimulating factor 1/MCSF/Csf1 produced by transfected human cells is a secreted protein with sequence (Gln33-Arg254) of Rat MCSF.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein
CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (Fc Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)CSF1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag,Biotin)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) proteinCSF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) proteinCSF1 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (mFc Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- MCSF
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背景
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Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
Synonyms: Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1 -
分子量
- 25.2 kDa
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UniProt
- Q8JZQ0
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途径
- RTK signaling
抗原
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