SERPINB5 Protein (AA 1-375, Ser176Pro-Mutant, Val66Ile-Mutant, Val187Leu-Mutant)
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- 抗原 See all SERPINB5 蛋白
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-375, Val66Ile-Mutant, Ser176Pro-Mutant, Val187Leu-Mutant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 纯度
- > 95 % by SDS-PAGE and HPLC analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product SERPINB5 蛋白
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serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (Active) protein
SERPINB5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (AA 1-231) protein (GST tag)SERPINB5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (AA 1-375) protein (Strep Tag)Crystallography grade SERPINB5 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) (AA 1-375) protein (Strep Tag)Crystallography grade SERPINB5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5) protein (Myc-DYKDDDDK Tag)SERPINB5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Maspin (rhMaspin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhMaspin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- 别名
- Maspin (SERPINB5 产品)
- 别名
- 1110036M19Rik Protein, AI462524 Protein, AI646751 Protein, Maspin Protein, PI-5 Protein, Spi7 Protein, ovalbumin Protein, PI5 Protein, maspin Protein, Pi5 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 5 Protein, serpin family B member 5 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog Protein, Serpinb5 Protein, SERPINB5 Protein, serpinb5.S Protein
- 背景
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Maspin is a non-inhibitory member of the serpin superfamily, a group of 40-60 kDa serine protease inhibitors. Maspin was discovered in 1994 and has been identified in prostate, thymus, testis, intestine, tongue, and lung. Recently Maspin received a great deal of attention due to its potential apoptotic role in cancers. Maspin expression predicts a better prognosis for several types of carcinomas including breast, prostate, colon, and oral squamus cell carcinoma. The level of Maspin is also inversely correlated to VEGF-A, an angiogenic factor. Researchers found that Maspin may play its apoptotic role as an endogenous inhibitor of histone deacetylase I (HDAC I). Therefore, Maspin is a potential personalized marker of Non-Small Cell Lung Carcinoma (NSCLC).Recombinant human Maspin (rhMaspin) produced in E. coli is a single non-glycosylated polypeptide chain containing 375 amino acids. rhMaspin has a molecular mass of 42.1 kDa analyzed by reducing SDS-PAGE.
Synonyms: Serpin B5, PI-5 - 分子量
- 42.1 kDa, observed by reducing SDS-PAGE.
- UniProt
- P36952
- 途径
- p53 Pathway
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