IL-6 Protein (AA 25-211)
-
- 抗原 See all IL-6 (IL6) 蛋白
- IL-6 (IL6) (Interleukin 6 (IL6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-211
-
宿主
- 大鼠
-
资源
- HEK-293T Cells
- 产品特性
- ED50 < 3 pg/mL, measured by a cell proliferation assay using 7TD1 Cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL6 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
-
- 抗原
- IL-6 (IL6) (Interleukin 6 (IL6))
- 别名
- Interleukin-6 (IL-6) (IL6 产品)
- 背景
-
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 - 分子量
- 21-26 kDa , observed by reducing SDS-PAGE.
- UniProt
- P20607
- 途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
-