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IL-10 Protein (AA 19-178, Arg25Lys-Mutant, Leu65Val-Mutant)

IL10 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN2018042
发货至: 中国
  • 抗原 See all IL-10 (IL10) 蛋白
    IL-10 (IL10) (Interleukin 10 (IL10))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 19-178, Arg25Lys-Mutant, Leu65Val-Mutant
    宿主
    • 21
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    大鼠
    资源
    • 31
    • 22
    • 18
    • 6
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    • 1
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    大肠杆菌(E. Coli)
    产品特性
    ED50 < 0.5 μg/mL, measured by a cell proliferation assay using C6 cells, corresponding to a specific activity of > 2.0x 10^3 units/mg.
    AA 19-178 (Arg25Lys, Leu65Val), expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL10 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant rat Interleukin-10 (IL-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, IL-10 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    IL-10 (IL10) (Interleukin 10 (IL10))
    别名
    Interleukin-10 (IL-10) (IL10 产品)
    别名
    CSIF Protein, GVHDS Protein, IL-10 Protein, IL10A Protein, TGIF Protein, Il-10 Protein, IL10X Protein, interleukin 10 Protein, IL10 Protein, Il10 Protein
    背景
    Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine produced by a variety of cell lines including T-cells, macrophages and mast cells. IL-10 is classified as a class-2 cytokine, a set of cytokines including IL-19, IL-20, IL-22, IL-24, and IL-26. IL-10 can inhibit the synthesis of pro-inflammatory cytokines such as IFN-gamma, IL-2, IL-3, TNF and GM-CSF. It also stimulates Th2 responses, but suppresses the antigen-presentation capacity of antigen presenting cells.Recombinant rat Interleukin-10 (IL-10)produced in E. coli is a single non-glycosylated polypeptide chain containing 161 amino acids. A fully biologically active molecule, recombinant rat Interleukin-10 (IL-10) has a molecular mass of 18.7 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Cytokine synthesis inhibitory factor, CSIF, TGIF, IL10A
    分子量
    18.7 kDa, observed by reducing SDS-PAGE.
    UniProt
    P29456
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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