IL-1 beta Protein (AA 117-269)
Quick Overview for IL-1 beta Protein (AA 117-269) (ABIN2018033)
抗原
See all IL-1 beta (IL1B) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 117-269
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产品特性
- ED50< 10 pg/mL, measured in a cell proliferation assay using D10S cells, corresponding to a specific activity of >1 x 10^8 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag)
IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 1, beta (IL1B) (AA 117-269) protein (His-Avi Tag,Biotin)IL1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Interleukin 1, beta (IL1B) (AA 1-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 1, beta (IL1B) (AA 117-269) protein (Fc Tag)IL1B 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1, beta (IL1B) (AA 106-267) protein (His tag)IL1B 宿主: 小鸡 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 114-266) protein (His tag)IL1B 宿主: 山羊 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 115-266) protein (His tag)IL1B 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 116-268) protein (His tag)IL1B 宿主: 马 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 115-267) protein (His tag)IL1B 宿主: Pig 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1, beta (IL1B) (AA 170-269) protein (GST tag)IL1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant human Interleukin 1 beta (IL-1 beta) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-1 beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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别名
- Interleukin-1 beta (IL-1 Beta)
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背景
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Interleukin 1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.
Synonyms: Catabolin, Interleukin-1 beta, IL1F2 -
分子量
- 17kDa, observed by non-reducing SDS-PAGE.
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NCBI登录号
- NP_000567
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途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
抗原
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