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Betacellulin Protein (BTC) (AA 32-111)

BTC 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analysis. Active
产品编号 ABIN2017690
发货至: 中国
  • 抗原 See all Betacellulin (BTC) 蛋白
    Betacellulin (BTC)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 32-111
    宿主
    • 14
    • 6
    • 3
    • 2
    • 2
    小鼠
    资源
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    大肠杆菌(E. Coli)
    产品特性
    ED50 <0.5 ng/mL, measured by a cell proliferation assay using3T3cells, corresponding to a specific activity of>2× 10^6 units/mg.
    AA 32-111, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE analysis.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product BTC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against 50 mM Tris, 300 mM NaCl, pH 9.0.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouse Betacellulin (rmBetacellulin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmBetacellulin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    Betacellulin (BTC)
    别名
    Betacellulin (BTC 产品)
    别名
    BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
    背景
    Betacellulin is a pleiotropic cytokine that belongs to the Epidermal Growth Factor (EGF) family. Like other members of the EGF family, Betacellulin possesses a conserved sequence of 35-40 amino acids which contain 3 disulfide bonds formed by 6 cysteines. Betacellulin is unique in the EGF family since it can bind and activate a broad spectrum of ErbB receptors. Functionally, Betacellulin plays a role in the development of the pancreas by activating signaling pathways beneficial for the function, survival and regeneration of pancreatic beta-cells. Additionally, Betacellulin has potential angiogenic activities and is important for the growth, development and repair of certain tissues.Recombinant mouse Betacellulin (rmBetacellulin) produced in E. coli is a single non-glycosylated polypeptide chain containing 81 amino acids. A fully biologically active molecule, rmBetacellulin has a molecular mass of 9.2 kDa analyzed by reducing SDS-PAGE.
    Synonyms: BTC
    分子量
    9.2 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q05928
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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