Betacellulin Protein (BTC) (AA 32-111)
-
- 抗原 See all Betacellulin (BTC) 蛋白
- Betacellulin (BTC)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 32-111
-
宿主
- 小鼠
-
资源
- 大肠杆菌(E. Coli)
- 产品特性
-
ED50 <0.5 ng/mL, measured by a cell proliferation assay using3T3cells, corresponding to a specific activity of>2× 10^6 units/mg.
AA 32-111, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product BTC 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 50 mM Tris, 300 mM NaCl, pH 9.0.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant mouse Betacellulin (rmBetacellulin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmBetacellulin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
-
- 抗原
- Betacellulin (BTC)
- 别名
- Betacellulin (BTC 产品)
- 别名
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- 背景
-
Betacellulin is a pleiotropic cytokine that belongs to the Epidermal Growth Factor (EGF) family. Like other members of the EGF family, Betacellulin possesses a conserved sequence of 35-40 amino acids which contain 3 disulfide bonds formed by 6 cysteines. Betacellulin is unique in the EGF family since it can bind and activate a broad spectrum of ErbB receptors. Functionally, Betacellulin plays a role in the development of the pancreas by activating signaling pathways beneficial for the function, survival and regeneration of pancreatic beta-cells. Additionally, Betacellulin has potential angiogenic activities and is important for the growth, development and repair of certain tissues.Recombinant mouse Betacellulin (rmBetacellulin) produced in E. coli is a single non-glycosylated polypeptide chain containing 81 amino acids. A fully biologically active molecule, rmBetacellulin has a molecular mass of 9.2 kDa analyzed by reducing SDS-PAGE.
Synonyms: BTC - 分子量
- 9.2 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q05928
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-