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PCSK1 Protein (AA 1-753) (GST tag)

PCSK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1989721
发货至: 中国
  • 抗原 See all PCSK1 蛋白
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-753
    宿主
    • 4
    • 3
    • 2
    资源
    • 4
    • 2
    • 1
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    • 1
    小麦胚
    标记
    This PCSK1 protein is labelled with GST tag.
    应用范围
    Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
    原理
    PCSK1 (Human) Recombinant Protein (P01)
    序列
    MERRAWSLQC TAFVLFCAWC ALNSAKAKRQ FVNEWAAEIP GGPEAASAIA EELGYDLLGQ IGSLENHYLF KHKNHPRRSR RSAFHITKRL SDDDRVIWAE QQYEKERSKR SALRDSALNL FNDPMWNQQW YLQDTRMTAA LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRS VPEKKECVVK DNDFEPRALK ANGEVIIEIP TRACEGQENA IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN WDFMSVHTWG ENPIGTWTLR ITDMSGRIQN EGRIVNWKLI LHGTSSQPEH MKQPRVYTSY NTVQNDRRGV EKMVDPGEEQ PTQENPKENT LVSKSPSSSS VGGRRDELEE GAPSQAMLRL LQSAFSKNSP PKQSPKKSPS AKLNIPYENF YEALEKLNKP SQLKDSEDSL YNDYVDVFYN TKPYKHRDDR LLQALVDILN EEN
    产品特性
    Human PCSK1 full-length ORF (NP_000430.3, 1 a.a. - 753 a.a.) recombinant protein with GST tag at N-terminal.
    纯化方法
    in vitro wheat germ expression system
    Top Product
    Discover our top product PCSK1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -80 °C
    储存方法
    Best use within three months from the date of receipt of this protein.
  • 抗原
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    别名
    PCSK1 (PCSK1 产品)
    别名
    BMIQ12 Protein, NEC1 Protein, PC1 Protein, PC3 Protein, SPC3 Protein, Nec-1 Protein, Nec1 Protein, Phpp-1 Protein, BDP Protein, PC1/3 Protein, proprotein convertase subtilisin/kexin type 1 Protein, prohormone convertase 1 Protein, PCSK1 Protein, Pcsk1 Protein, pcsk1 Protein, PC1B Protein
    背景
    Synonyms: BMIQ12,NEC1,PC1,PC3,SPC3
    Gene Description: proprotein convertase subtilisin/kexin type 1
    Gene Name: PCSK1
    Gene Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.
    分子量
    110.6 kDa (theoreatical)
    基因ID
    5122
    NCBI登录号
    NM_000439
    途径
    Peptide Hormone Metabolism
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