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IL-1 beta Protein (AA 1-586)

This Recombinant IL-1 beta protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1945600
发货至: 中国
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Quick Overview for IL-1 beta Protein (AA 1-586) (ABIN1945600)

抗原

See all IL-1 beta (IL1B) 蛋白
IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-586

    原理

    Recombinant Human Ezrin/EZR/VIL2

    序列

    MPKPINVRVT TMDAELEFAI QPNTTGKQLF DQVVKTIGLR EVWYFGLHYV DNKGFPTWLK LDKKVSAQEV RKENPLQFKF RAKFYPEDVA EELIQDITQK LFFLQVKEGI LSDEIYCPPE TAVLLGSYAV QAKFGDYNKE VHKSGYLSSE RLIPQRVMDQ HKLTRDQWED RIQVWHAEHR GMLKDNAMLE YLKIAQDLEM YGINYFEIKN KKGTDLWLGV DALGLNIYEK DDKLTPKIGF PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LQLCMGNHEL YMRRRKPDTI EVQQMKAQAR EEKHQKQLER QQLETEKKRR ETVEREKEQM MREKEELMLR LQDYEEKTKK AERELSEQIQ RALQLEEERK RAQEEAERLE ADRMAALRAK EELERQAVDQ IKSQEQLAAE LAEYTAKIAL LEEARRRKED EVEEWQHRAK EAQDDLVKTK EELHLVMTAP PPPPPPVYEP VSYHVQESLQ DEGAEPTGYS AELSSEGIRD DRNEEKRITE AEKNERVQRQ LLTLSSELSQ ARDENKRTHN DIIHNENMRQ GRDKYKTLRQ IRQGNTKQRI DEFEAL

    产品特性

    Recombinant Human Ezrin is produced by our E.coli expression system and the target gene encoding Met1-Leu586 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Supplied as a 0.2 um filtered solution of 10 mM HEPES, pH 7.4.

    注意事项

    minimize freeze-thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    别名

    Interleukin-1 beta/catabolin

    背景

    Alternative Names: Ezrin, Cytovillin, Villin-2, p81, EZR, VIL2IL1B is a 269 amino acids protein which belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.

    分子量

    69.4kDa

    UniProt

    P15311

    途径

    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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