CPE Protein (AA 42-453) (His tag)
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- 抗原 See all CPE 蛋白
- CPE (Carboxypeptidase E (CPE))
- 蛋白类型
- Recombinant
- 产品特性
- AA 42-453
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宿主
- 人
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资源
- 人细胞
- 标记
- This CPE protein is labelled with His tag.
- 原理
- Recombinant Human Carboxypeptidase E/CPE (C-6His)
- 序列
- RLQQEDGISF EYHRYPELRE ALVSVWLQCT AISRIYTVGR SFEGRELLVI ELSDNPGVHE PGEPEFKYIG NMHGNEAVGR ELLIFLAQYL CNEYQKGNET IVNLIHSTRI HIMPSLNPDG FEKAASQPGE LKDWFVGRSN AQGIDLNRNF PDLDRIVYVN EKEGGPNNHL LKNMKKIVDQ NTKLAPETKA VIHWIMDIPF VLSANLHGGD LVANYPYDET RSGSAHEYSS SPDDAIFQSL ARAYSSFNPA MSDPNRPPCR KNDDDSSFVD GTTNGGAWYS VPGGMQDFNY LSSNCFEITV ELSCEKFPPE ETLKTYWEDN KNSLISYLEQ IHRGVKGFVR DLQGNPIANA TISVEGIDHD VTSAKDGDYW RLLIPGNYKL TASAPGYLAI TKKVAVPYSP AAGVDFELES FSVDHHHHHH
- 产品特性
- Recombinant Human Carboxypeptidase E/CPE is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg42-Ser453) of Human CPE fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CPE 蛋白
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Carboxypeptidase E (CPE) (AA 43-476) protein (His tag)
CPE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Carboxypeptidase E (CPE) (AA 211-325) protein (GST tag)CPE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Carboxypeptidase E (CPE) (AA 43-476) protein (His tag)Crystallography grade CPE 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Carboxypeptidase E (CPE) (AA 43-476) protein (His tag)Crystallography grade CPE 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM ZnCl2,10 % Glycerol, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- CPE (Carboxypeptidase E (CPE))
- 别名
- CPE (CPE 产品)
- 别名
- CPE Protein, CPH Protein, Cph-1 Protein, Cph1 Protein, R74677 Protein, fat Protein, CARBE Protein, Cph Protein, si:ch211-198g9.2 Protein, zgc:85981 Protein, carboxypeptidase E Protein, carboxypeptidase E L homeolog Protein, CPE Protein, cpe Protein, Cpe Protein, cpe.L Protein
- Sub Type
- Fusionprotein
- 背景
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The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
Alternative Names: Carboxypeptidase E(CPE for short), also called Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase, is a peripheral membrane protein and a zinc metallo carboxypeptidase which belongs to the peptidase M14 family. - 分子量
- 47.1 kDa
- UniProt
- P16870
- 途径
- Peptide Hormone Metabolism, Synaptic Membrane
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