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CPE Protein (His tag)

CPE 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318246
发货至: 中国
  • 抗原 See all CPE 蛋白
    CPE (Carboxypeptidase E (CPE))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    人细胞
    标记
    This CPE protein is labelled with His tag.
    原理
    Recombinant Human Carboxypeptidase E/CPE Protein (His Tag)
    序列
    Arg42-Ser453
    产品特性
    Recombinant Human Carboxypeptidase E is produced by our Mammalian expression system and the target gene encoding Arg42-Ser453 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CPE 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM ZnCl2,10 % Glycerol, pH 7.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    CPE (Carboxypeptidase E (CPE))
    别名
    Carboxypeptidase E/CPE (CPE 产品)
    别名
    CPE Protein, CPH Protein, Cph-1 Protein, Cph1 Protein, R74677 Protein, fat Protein, CARBE Protein, Cph Protein, si:ch211-198g9.2 Protein, zgc:85981 Protein, carboxypeptidase E Protein, carboxypeptidase E L homeolog Protein, CPE Protein, cpe Protein, Cpe Protein, cpe.L Protein
    背景

    Background: The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.

    Synonym: Carboxypeptidase E(CPE for short), Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase

    分子量
    47.1 kDa
    UniProt
    P16870
    途径
    Peptide Hormone Metabolism, Synaptic Membrane
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