ICOS Protein (AA 21-141) (Fc Tag)
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- 抗原 See all ICOS 蛋白
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-141
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宿主
- 人
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资源
- 人细胞
- 标记
- This ICOS protein is labelled with Fc Tag.
- 原理
- Recombinant Human ICOS/CRP-1/AILIM/CD278 (C-Fc)
- 序列
- EINGSANYEM FIFHNGGVQI LCKYPDIVQQ FKMQLLKGGQ ILCDLTKTKG SGNTVSIKSL KFCHSQLSNN SVSFFLYNLD HSHANYYFCN LSIFDPPPFK VTLTGGYLHI YESQLCCQLK FVDDIEGRMD EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR EEMTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK
- 产品特性
- Recombinant Human Inducible T-cell costimulator/ICOS is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu21-Phe141) of Human ICOS fused with a FC tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ICOS 蛋白
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Inducible T-Cell Co-Stimulator (ICOS) (AA 21-144) protein (Fc Tag)
ICOS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-141) protein (Fc Tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-134) protein (His tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys136Ser-Mutant), (Cys137Ser-Mutant) protein (His tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) (Cys137Ser-Mutant), (Cys138Ser-Mutant) protein (His tag)ICOS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS 宿主: 猕猴 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Inducible T-Cell Co-Stimulator (ICOS) (AA 1-168) protein (GST tag)ICOS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) protein (GST tag)ICOS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inducible T-Cell Co-Stimulator (ICOS) protein (mFc-His Tag)ICOS 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Inducible T-Cell Co-Stimulator (ICOS) protein (Fc Tag)ICOS 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- 别名
- ICOS (ICOS 产品)
- 别名
- ICOS Protein, AILIM Protein, CCLP Protein, CRP-1 Protein, H4 Protein, Ly115 Protein, CD278 Protein, CVID1 Protein, Ailim Protein, inducible T-cell costimulator Protein, inducible T cell co-stimulator Protein, inducible T-cell co-stimulator Protein, ICOS Protein, LOC100232284 Protein, Icos Protein
- Sub Type
- Fusionprotein
- 背景
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Inducible T-cell costimulator, also known as activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1 and ICOS, belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin, ICOS plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1, which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antige
Alternative Names: Inducible T-cell costimulator,activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1,ICOS, - 分子量
- 40.8 kDa
- UniProt
- Q9Y6W8
- 途径
- Cancer Immune Checkpoints
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