LMCD1 Protein (AA 1-365) (His tag)
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- 抗原 See all LMCD1 蛋白
- LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-365
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This LMCD1 protein is labelled with His tag.
- 原理
- Recombinant Human LIM and Cysteine-Rich Domains Protein 1/LMCD1/Dyxin (N, C-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MAKVAKDLNP GVKKMSLGQL QSARGVACLG CKGTCSGFEP HSWRKICKSC KCSQEDHCLT SDLEDDRKIG RLLMDSKYST LTARVKGGDG IRIYKRNRMI MTNPIATGKD PTFDTITYEW APPGVTQKLG LQYMELIPKE KQPVTGTEGA FYRRRQLMHQ LPIYDQDPSR CRGLLENELK LMEEFVKQYK SEALGVGEVA LPGQGGLPKE EGKQQEKPEG AETTAATTNG SLSDPSKEVE YVCELCKGAA PPDSPVVYSD RAGYNKQWHP TCFVCAKCSE PLVDLIYFWK DGAPWCGRHY CESLRPRCSG CDEIIFAEDY QRVEDLAWHR KHFVCEGCEQ LLSGRAYIVT KGQLLCPTCS KSKRSLEHHH HHH
- 产品特性
- Recombinant Human LIM and cysteine-rich domains protein 1/LMCD1/Dyxin is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser365) of Human LMCD1 fused with a 6His tag at the N-terminus and a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LMCD1 蛋白
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LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (His tag)
LMCD1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 1-365) protein (GST tag)LMCD1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LIM and Cysteine-Rich Domains 1 (LMCD1) (AA 266-364) protein (GST tag)LMCD1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LIM and Cysteine-Rich Domains 1 (LMCD1) protein (Myc-DYKDDDDK Tag)LMCD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
- 别名
- LMCD1 (LMCD1 产品)
- 别名
- LMCD1 Protein, AW455500 Protein, AW553074 Protein, dyxin Protein, LIM and cysteine rich domains 1 Protein, LIM and cysteine-rich domains 1 Protein, LMCD1 Protein, lmcd1 Protein, Lmcd1 Protein
- Sub Type
- Fusionprotein
- 背景
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LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Alternative Names: LIM and cysteine-rich domains protein 1, LMCD1, Dyxin - 分子量
- 44 kDa
- UniProt
- Q9NZU5
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