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LMCD1 Protein (His tag)

LMCD1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318737
发货至: 中国
  • 抗原 See all LMCD1 蛋白
    LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This LMCD1 protein is labelled with His tag.
    原理
    Recombinant Human LMCD1/Dyxin Protein (His Tag)
    序列
    Met 1-Ser365
    产品特性
    Recombinant Human LIM and cysteine-rich domains protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Ser365 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product LMCD1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
    别名
    LMCD1/Dyxin (LMCD1 产品)
    别名
    LMCD1 Protein, AW455500 Protein, AW553074 Protein, dyxin Protein, LIM and cysteine rich domains 1 Protein, LIM and cysteine-rich domains 1 Protein, LMCD1 Protein, lmcd1 Protein, Lmcd1 Protein
    背景

    Background: LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

    Synonym: LIM and cysteine-rich domains protein 1, LMCD1, Dyxin

    分子量
    44.0 kDa
    UniProt
    Q9NZU5
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