OBFC1 Protein (AA 1-368) (His tag)
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- 抗原 See all OBFC1 蛋白
- OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-368
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This OBFC1 protein is labelled with His tag.
- 原理
- Recombinant Human OBFC1/CST Complex Subunit STN1 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MQPGSSRCEE ETPSLLWGLD PVFLAFAKLY IRDILDMKES RQVPGVFLYN GHPIKQVDVL GTVIGVRERD AFYSYGVDDS TGVINCICWK KLNTESVSAA PSAARELSLT SQLKKLQETI EQKTKIEIGD TIRVRGSIRT YREEREIHAT AYYKVDDPVW NIQIARMLEL PTIYRKVYDQ PFHSSALEKE EALSNPGALD LPSLTSLLSE KAKEFLMENR VQSFYQQELE MVESLLSLAN QPVIHSACSD QVNFKKDTTS KAIHSIFKNA IQLLQEKGLV FQKDDGFDNL YYVTREDKDL HRKIHRIIQQ DCQKPNHMEK GCHFLHILAC ARLSIRPGLS EAVLQQVLEL LEDQSDIVST MEHYYTAF
- 产品特性
- Recombinant Human Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1/OBFC1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Phe368) of Human OBFC1 fused with a His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product OBFC1 蛋白
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Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) (AA 1-368) protein (His tag)
OBFC1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) (AA 1-368) protein (GST tag)OBFC1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) protein (Myc-DYKDDDDK Tag)OBFC1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
- 别名
- Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1/OBFC1 (OBFC1 产品)
- 别名
- AAF-44 Protein, AAF44 Protein, RP11-541N10.2 Protein, RPA-32 Protein, STN1 Protein, bA541N10.2 Protein, 0610009H20Rik Protein, 2310057J23Rik Protein, AI413458 Protein, zgc:64174 Protein, ATSTN1 Protein, F10K1.17 Protein, F10K1_17 Protein, STN1, CST complex subunit Protein, Nucleic acid-binding, OB-fold-like protein Protein, STN1 Protein, Stn1 Protein, stn1 Protein
- Sub Type
- Fusionprotein
- 背景
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CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Alternative Names: CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1 - 分子量
- 44.2 kDa
- UniProt
- Q9H668
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