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Cytochrome C Protein (AA 2-105) (His tag)

CYCS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1692193
发货至: 中国
  • 抗原 See all Cytochrome C (CYCS) 蛋白
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    蛋白类型
    Recombinant
    产品特性
    AA 2-105
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    资源
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    大肠杆菌(E. Coli)
    标记
    This Cytochrome C protein is labelled with His tag.
    原理
    Recombinant Human Cytochrome C/CYCS (C-6His)
    序列
    GDVEKGKKIF IMKCSQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGYSYTA ANKNKGIIWG EDTLMEYLEN PKKYIPGTKM IFVGIKKKEE RADLIAYLKK ATNELEHHHH HH
    产品特性
    Recombinant Human Cytochrome C/CYCS is produced with our E. coli expression system. The target protein is expressed with sequence (Gly2-Glu105) of Human CYCS fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CYCS 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.15M NaCl, 20 % Glycerol, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    别名
    CYCS (CYCS 产品)
    别名
    CYC Protein, HCS Protein, THC4 Protein, cyct Protein, cyc Protein, hcs Protein, CYCS Protein, cytc Protein, CYCSA Protein, CG17903 Protein, Cyt C Protein, Cyt c Protein, Cyt-c2 Protein, CytC-2 Protein, Cytc Protein, Cytc-p Protein, DC4 Protein, DMc01 Protein, Dmel\\CG17903 Protein, cyt c Protein, cyt c-p Protein, cyt-c-p Protein, cyt-c2 Protein, cyt.c Protein, cytochrome c Protein, dc4 Protein, pDMc01 Protein, wu:fk52b01 Protein, zgc:86706 Protein, ENSMUSG00000058927 Protein, cytochrome c, somatic Protein, cytochrome c, somatic S homeolog Protein, Cytochrome c proximal Protein, cytochrome c, somatic b Protein, cytochrome c, somatic pseudogene Protein, cytochrome c-like Protein, cytochrome c Protein, CYCS Protein, cycs.S Protein, cycs Protein, Cycs Protein, Cyt-c-p Protein, cycsb Protein, Gm10053 Protein, LOC100724240 Protein, CYC Protein, LOC100847700 Protein, LOC101107954 Protein, LOC106829744 Protein, LOC106992390 Protein, LOC102085712 Protein
    Sub Type
    Fusionprotein
    背景
    Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
    Alternative Names: Cytochrome C, CYCS, CYC
    分子量
    12.8 kDa
    UniProt
    P99999
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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