UPP1 Protein (AA 1-173) (His tag)
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- 抗原 See all UPP1 蛋白
- UPP1 (Uridine Phosphorylase 1 (UPP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-173
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This UPP1 protein is labelled with His tag.
- 原理
- Recombinant Human Uridine Phosphorylase 1/UPP1 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MQRKLKVTSL EPGTVVITEQ AVDTCFKAEF EQIVLGKRVI RKTDLNKKLV QELLLCSAEL SEFTTVVGNT MCTLDFYEGQ GRLDGALCSY TEKDKQAYLE AAYAAGVRNI EMESSVFAAM CSACGLQAAV VCVTLLNRLE GDQISSPRNV LSEYQQRPQR LVSYFIKKKL SKA
- 产品特性
- Recombinant Human Uridine Phosphorylase 1/UPP1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala173) of Human UPP1 fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product UPP1 蛋白
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Uridine Phosphorylase 1 (UPP1) (AA 1-173) protein (His tag)
UPP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Uridine Phosphorylase 1 (UPP1) (AA 1-310) protein (His tag)UPP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Uridine Phosphorylase 1 (UPP1) (AA 1-92) protein (GST tag)UPP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Uridine Phosphorylase 1 (UPP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UPP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Uridine Phosphorylase 1 (UPP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)UPP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 1 mM DTT, pH 8.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- UPP1 (Uridine Phosphorylase 1 (UPP1))
- 别名
- Uridine Phosphorylase 1/UPP1 (UPP1 产品)
- 别名
- upp1 Protein, UDRPASE Protein, UP Protein, UPASE Protein, UPP Protein, im:6911242 Protein, zgc:110755 Protein, AI325217 Protein, UPase Protein, UdRPase Protein, Up Protein, Upp Protein, uridine phosphorylase 1 Protein, uridine phosphorylase Protein, upp1 Protein, NP_RS08675 Protein, Tsp_02326 Protein, UPP1 Protein, Upp1 Protein
- Sub Type
- Fusionprotein
- 背景
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Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.
Alternative Names: UPP1 Protein, Uridine Phosphorylase 1, UPP1 - 分子量
- 21.3 kDa
- UniProt
- Q86Y75
- 途径
- Ribonucleoside Biosynthetic Process
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