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UPP1 Protein (His tag)

This Recombinant UPP1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7319161
发货至: 中国
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Quick Overview for UPP1 Protein (His tag) (ABIN7319161)

抗原

See all UPP1 蛋白
UPP1 (Uridine Phosphorylase 1 (UPP1))

蛋白类型

Recombinant

宿主

  • 11
  • 2
  • 1
  • 1

资源

  • 9
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  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This UPP1 protein is labelled with His tag.

    原理

    Recombinant Human UPP1 Protein (His Tag)

    序列

    Met 1-Ala173

    产品特性

    Recombinant Human Uridine Phosphorylase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala173 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 1 mM DTT, pH 8.0.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    UPP1 (Uridine Phosphorylase 1 (UPP1))

    别名

    UPP1

    背景

    Background: Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.

    Synonym: UPP1 Protein, Uridine Phosphorylase 1, UPP1

    分子量

    21.3 kDa

    UniProt

    Q86Y75

    途径

    Ribonucleoside Biosynthetic Process
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