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UPP1 Protein (His tag)

UPP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319161
发货至: 中国
  • 抗原 See all UPP1 蛋白
    UPP1 (Uridine Phosphorylase 1 (UPP1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    • 1
    资源
    • 6
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This UPP1 protein is labelled with His tag.
    原理
    Recombinant Human UPP1 Protein (His Tag)
    序列
    Met 1-Ala173
    产品特性
    Recombinant Human Uridine Phosphorylase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala173 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product UPP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 1 mM DTT, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    UPP1 (Uridine Phosphorylase 1 (UPP1))
    别名
    UPP1 (UPP1 产品)
    别名
    upp1 Protein, UDRPASE Protein, UP Protein, UPASE Protein, UPP Protein, im:6911242 Protein, zgc:110755 Protein, AI325217 Protein, UPase Protein, UdRPase Protein, Up Protein, Upp Protein, uridine phosphorylase 1 Protein, uridine phosphorylase Protein, upp1 Protein, NP_RS08675 Protein, Tsp_02326 Protein, UPP1 Protein, Upp1 Protein
    背景

    Background: Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.

    Synonym: UPP1 Protein, Uridine Phosphorylase 1, UPP1

    分子量
    21.3 kDa
    UniProt
    Q86Y75
    途径
    Ribonucleoside Biosynthetic Process
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