STAT3 Protein (AA 1-175) (His tag)
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- 抗原 See all STAT3 蛋白
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-175
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This STAT3 protein is labelled with His tag.
- 原理
- Recombinant Human Signal Transducer and Activator of Transcription 3/STAT3 (C-6His)
- 序列
- MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE SHATLVFHNL LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD VRKRVQDLEQ KMKVVENLQD DFDFNLEHHH HHH
- 产品特性
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Recombinant Human Signal Transducer and Activator of Transcription 3/STAT3 (C-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product STAT3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
- 别名
- Signal Transducer and Activator of Transcription 3/STAT3 (STAT3 产品)
- 别名
- 1110034C02Rik Protein, AW109958 Protein, Aprf Protein, APRF Protein, HIES Protein, Xstat3 Protein, aprf Protein, hies Protein, stat3 Protein, wu:fc15d02 Protein, wu:fl59g06 Protein, z-Stat3 Protein, signal transducer and activator of transcription 3 Protein, signal transduction and activation of transcription 3 Protein, signal transducer and activator of transcription 3, gene 1 L homeolog Protein, signal transducer and activator of transcription 3 (acute-phase response factor) Protein, STAT3 Protein, stat3 Protein, Stat3 Protein, stat3.1.L Protein
- 背景
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Recombinant Human Signal Transducer and Activator of Transcription 3/STAT3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn175) of Human STAT3 fused with a 6His tag at the C-terminus.
Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. - 分子量
- 21.8 kDa
- UniProt
- P40763
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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