CDC37 Protein (His tag)
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- 抗原 See all CDC37 蛋白
- CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CDC37 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS), Western Blotting (WB), Functional Studies (Func)
- 序列
- MGHHHHHHMV DYSVWDHIEV SDDEDETHPN IDTASLFRWR HQARVERMEQ FQKEKEELDR GCRECKRKVA ECQRKLKELE VAEGGKAELE RLQAEAQQLR KEERSWEQKL EEMRKKEKSM PWNVDTLSKD GFSKSMVNTK PEKTEEDSEE VREQKHKTFV EKYEKQIKHF GMLRRWDDSQ KYLSDNVHLV CEETANYLVI WCIDLEVEEK CALMEQVAHQ TIVMQFILEL AKSLKVDPRA CFRQFFTKIK TADRQYMEGF NDELEAFKER VRGRAKLRIE KAMKEYEEEE RKKRLGPGGL DPVEVYESLP EELQKCFDVK DVQMLQDAIS KMDPTDAKYH MQRCIDSGLW VPNSKASEAK EGEEAGPGDP LLEAVPKTGD EKDVSV
- 特异性
- ~44.5 kDa
- 产品特性
- 4 µM SPR-304, when added to 2 µM SPR-300 (Aha1)-activated Hsp90 (2 µM, His-tagged Hsp90 beta) in 33 mM Hepes pH 7.2, 30 mM NaCl, 5 mM MgCl2, 1 mM DTT, 1.5 mM ATP in a 100 µL reaction at 37 degrees C, eliminated all Aha1-mediated ATPase stimulation as well as intrinsic Hsp90 ATPase activity. (This is an enzyme-linked ATP regeneration assay tracking loss of NADH absorbance at 340nm).
- 纯化方法
- Affinity Purified
- 纯度
- >90%
- Top Product
- Discover our top product CDC37 蛋白
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Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) protein (His tag)
CDC37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) protein (GST tag)CDC37 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) protein (GST tag,His tag)CDC37 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) proteinCDC37 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-378) protein (Strep Tag)Crystallography grade CDC37 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 1-379) protein (Strep Tag)Crystallography grade CDC37 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 2-378) protein (His tag)Crystallography grade CDC37 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) (AA 2-379) protein (His tag)Crystallography grade CDC37 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37) protein (Myc-DYKDDDDK Tag)CDC37 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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This product has been certified >90% pure using SDS PAGE analysis.
- 限制
- 仅限研究用
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- 浓度
- Lot specific
- 缓冲液
- 25 mM Tris buffer pH 7.2, 150 mM NaCl, 0.1DTT, 50 % glycerol
- 储存条件
- -20 °C
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- 抗原
- CDC37 (Cell Division Cycle 37 Homolog (S. Cerevisiae) (CDC37))
- 别名
- CDC37 (CDC37 产品)
- 别名
- CG12019 Protein, CPDR-1 Protein, CPDR-2 Protein, DROCPDR Protein, Dmel\\CG12019 Protein, E(sev)3B Protein, cdc37 Protein, Afu4g10010 Protein, P50CDC37 Protein, p50 Protein, p50Cdc37 Protein, CG12019 gene product from transcript CG12019-RA Protein, cell division cycle 37 homolog Protein, Hsp90 co-chaperone Cdc37 Protein, Cdc37p Protein, cell division cycle 37 Protein, Cdc37 Protein, cdc37 Protein, AFUA_4G10010 Protein, CDC37 Protein
- 背景
- HSP90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with HSP90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing HSP90 to its target kinases (1, 2). CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies (3, 4).
- 分子量
- Approx. 44.5 kDa
- 基因ID
- 11140
- NCBI登录号
- NP_008996
- UniProt
- Q16543
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