PARK7/DJ1 Protein (AA 1-188, partial) (GST tag)
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- 抗原 See all PARK7/DJ1 (PARK7) 蛋白
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-188, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PARK7/DJ1 protein is labelled with GST tag.
- 应用范围
- ELISA
- 序列
- MASKRALVIL AKGAEEMETV IPVDVMRRAG IKVTVAGLAG KDPVQCSRDV VICPDASLED AKKEGPYDVV VLPGGNLGAQ NLSESAAVKE ILKEQENRKG LIAAICAGPT ALLAHEIGFG SKVTTHPLAK DKMMNGGHYT YSENRVEKDG LILTSRGPGT SFEFALAIVE ALNGKEVAAQ VKAPLVLK
- 产品特性
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- 纯度
- 95 %
- Top Product
- Discover our top product PARK7 蛋白
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Parkinson Protein 7 (PARK7) (AA 1-189) protein (GST tag)
PARK7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Parkinson Protein 7 (PARK7) (AA 1-100) protein (GST tag)PARK7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Parkinson Protein 7 (PARK7) proteinPARK7 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % SDS, WB, ELISA, IP
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- 说明
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The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- 0.2-2 mg/mL
- 缓冲液
- Tris-based buffer, 50 % glycerol
- 注意事项
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
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- 抗原
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- 别名
- Protein DJ-1 protein (PARK7 产品)
- 别名
- DJ-1 Protein, DJ1 Protein, CAP1 Protein, Dj1 Protein, SP22 Protein, dj1 Protein, zgc:103725 Protein, park7b Protein, park7 Protein, park7a Protein, Parkinsonism associated deglycase Protein, Parkinson disease (autosomal recessive, early onset) 7 Protein, parkinson protein 7 Protein, parkinson protein 7 S homeolog Protein, parkinson protein 7 L homeolog Protein, PARK7 Protein, Park7 Protein, park7 Protein, park7.S Protein, park7.L Protein
- 背景
- Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Stabilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7B and inhibits its deubiquitinating activity. Enhances RELA nuclear translocation. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone
- 分子量
- 47.2 kD
- UniProt
- Q99497
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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