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IL-2 蛋白

IL2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % by SDS-PAGE. Visualized by silver stain Active
产品编号 ABIN1589645
发货至: 中国
  • 抗原 See all IL-2 (IL2) 蛋白
    IL-2 (IL2) (Interleukin 2 (IL2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 29
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    资源
    • 41
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    大肠杆菌(E. Coli)
    序列
    MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLHYKDPAA NKARKEAELA AATAEQ
    产品特性
    Length (AA): 156
    Chromosomal location: 4q26-q27
    The ED50 as determined by the dose-dependent stimulation of proliferation of murine D10G4.1 cells is in the range of 0.1-0.5 ng/mL.
    纯度
    > 98 % by SDS-PAGE. Visualized by silver stain
    内毒素水平
    < 0.1 ng per µg of IL-2
    Top Product
    Discover our top product IL2 蛋白
  • 说明

    Cytokines & Growth Factors

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    The lyophilized IL-2 should be reconstituted in 50 mM acetic acid to a concentration not less than 100 μg/mL. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.
    缓冲液
    50 mM acetic acid
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    0 °C
    储存方法
    The lyophilized IL-2, though stable at room temperature, is best stored desiccated below 0 °C. Reconstituted IL-2 should be stored in workingaliquots at -20 °C.
  • Haustein, Ramer, Linnebacher, Manda, Hinz: "Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1." in: Biochemical pharmacology, Vol. 92, Issue 2, pp. 312-25, (2014) (PubMed).

  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    IL-2 (IL2 产品)
    别名
    IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
    背景
    IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 (modified at the C-terminal end) is a 15.5 kDa protein, containing 156 amino acid residues including one intrachain disulfide bond.
    Synonyms: IL2, IL-2, TCGF, lymphokine
    分子量
    15.5 kDa
    NCBI登录号
    NP_000577, NM_000586
    UniProt
    P60568
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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