电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Granulin Protein (GRN) (AA 494-593) (GST tag)

GRN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
产品编号 ABIN1355792
发货至: 中国
  • 抗原 See all Granulin (GRN) 蛋白
    Granulin (GRN)
    蛋白类型
    Recombinant
    产品特性
    AA 494-593
    宿主
    • 14
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 9
    • 7
    • 7
    • 3
    • 1
    小麦胚
    标记
    This Granulin protein is labelled with GST tag.
    应用范围
    Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
    原理
    GRN (Human) Recombinant Protein (Q01)
    序列
    SCEKEVVSAQ PATFLARSPH VAVKDVECGE GHFCHDNQTC CRDNRQGWAC CPYRQGVCCA DRRHCCPAGF RCAARGTKCL RREAPRWDAP LRDPALRQLL
    产品特性
    Human GRN partial ORF ( NP_002078, 494 a.a. - 593 a.a.) recombinant protein with GST-tag at N-terminal.
    纯化方法
    in vitro wheat germ expression system
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    限制
    仅限研究用
  • 缓冲液
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -80 °C
    储存方法
    Best use within three months from the date of receipt of this protein.
  • Chen, Chang, Deng, Xu, Nguyen, Martens, Cenik, Taylor, Hudson, Chung, Yu, Yu, Herz, Farese, Kukar, Tansey: "Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 21, pp. 9202-13, (2013) (PubMed).

    De Muynck, Herdewyn, Beel, Scheveneels, Van Den Bosch, Robberecht, Van Damme: "The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding." in: Neurobiology of aging, Vol. 34, Issue 11, pp. 2541-7, (2013) (PubMed).

    Van Damme, Van Hoecke, Lambrechts, Vanacker, Bogaert, van Swieten, Carmeliet, Van Den Bosch, Robberecht: "Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival." in: The Journal of cell biology, Vol. 181, Issue 1, pp. 37-41, (2008) (PubMed).

  • 抗原
    Granulin (GRN)
    别名
    GRN (GRN 产品)
    别名
    GRN Protein, grn Protein, wu:fb11g12 Protein, wu:fj18f05 Protein, MGC53354 Protein, DKFZp459H066 Protein, CLN11 Protein, GEP Protein, GP88 Protein, PCDGF Protein, PEPI Protein, PGRN Protein, epithelin Protein, acrogranin Protein, granulin precursor Protein, granulin a Protein, Granulins Protein, granulin L homeolog Protein, granulin Protein, GRN Protein, grna Protein, grn Protein, grn.L Protein, granulin Protein, ORF1 granulin Protein, Grn Protein
    背景
    Full Gene Name: granulin
    Synonyms: GEP,GP88,PCDGF,PEPI,PGRN
    基因ID
    2896
    NCBI登录号
    NM_002087
You are here:
客服