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IL-1 beta Protein (AA 118-269)
IL1B
宿主: 小鼠
宿主: 大肠杆菌(E. Coli)
Recombinant
>95 % (SDS-PAGE)
SDS
产品细节
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抗原
See all IL-1 beta (IL1B) 蛋白
IL-1 beta (IL1B)
(Interleukin 1, beta (IL1B))
蛋白类型
Recombinant
产品特性
AA 118-269
宿主
All origins for IL-1 beta 蛋白
小鼠
资源
All sources for IL-1 beta 蛋白
大肠杆菌(E. Coli)
应用范围
SDS-PAGE (SDS)
特异性
Binds to mouse IL-1R.
交叉反应
小鼠
产品特性
Mouse IL-1beta (aa 118-269) is untagged.
纯度
>95 % (SDS-PAGE)
内毒素水平
<0.1EU/μg purified protein (LAL test, Lonza).
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Lyophilized
溶解方式
Reconstitute with 100 μL sterile water.
浓度
Lot specific
缓冲液
Lyophilized. Contains PBS.
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
有效期
6 months
目标详细情况
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抗原
IL-1 beta (IL1B)
(Interleukin 1, beta (IL1B))
别名
IL-1beta (IL1B 产品 )
别名
IL-1 Protein, IL1-BETA Protein, IL1F2 Protein, IL-1BETA Protein, IL1beta Protein, il1-b Protein, zgc:111873 Protein, IL-1B Protein, IL-1beta Protein, Il-1b Protein, IL1B Protein, IL-1 beta Protein, IL-1b Protein, interleukin 1 beta Protein, interleukin 1, beta Protein, IL1B Protein, il1b Protein, Il1b Protein
背景
IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
分子量
~17kDa (SDS-PAGE)
UniProt
P01584
途径
NF-kappaB Signaling , Interferon-gamma Pathway , TLR signaling , Negative Regulation of Hormone Secretion , Cellular Response to Molecule of Bacterial Origin , Carbohydrate Homeostasis , Glycosaminoglycan Metabolic Process , Myometrial Relaxation and Contraction , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Autophagy , Cancer Immune Checkpoints , Inflammasome
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