ULBP2 Protein (His tag)
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- 抗原 See all ULBP2 蛋白
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ULBP2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product ULBP2 蛋白
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UL16 Binding Protein 2 (ULBP2) (AA 26-217) protein (His-Avi Tag)
ULBP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
UL16 Binding Protein 2 (ULBP2) protein (His-Avi Tag,Biotin)ULBP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
UL16 Binding Protein 2 (ULBP2) (AA 25-224) protein (His tag)ULBP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
UL16 Binding Protein 2 (ULBP2) (AA 1-246) protein (GST tag)ULBP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 说明
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Synonyms: NKG2D ligand 2, N2DL2, RAET1H
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 2 M Urea, 0.2 M NaCl, 2 mM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- 别名
- ULBP2 (ULBP2 产品)
- 别名
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- 背景
- ULBP2, also known as NKG2D ligand 2, belongs to the MHC class I family. This protein is ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human ULBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 24.3 kDa (216aa)
- NCBI登录号
- NP_079493
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