ULBP2 Protein (AA 26-217) (His-Avi Tag)
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- 抗原 See all ULBP2 蛋白
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-217
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ULBP2 protein is labelled with His-Avi Tag.
- 原理
- Human ULBP-2 Protein
- 序列
- Gly26-Ser217
- 产品特性
- Recombinant Human ULBP-2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly26-Ser217.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human ULBP-2, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.26μg/ml determined by ELISA. See testing image for detail.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- 别名
- ULBP-2 (ULBP2 产品)
- 别名
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- 背景
- ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
- 分子量
- 24.6 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9BZM5
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