ERCC1 Protein (His tag)
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- 抗原 See all ERCC1 蛋白
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This ERCC1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by using conventional chromatography.
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ERCC1 蛋白
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- 说明
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Synonyms: DNA excision repair protein ERCC-1, COFS4, RAD10, UV20
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, 1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
- 别名
- ERCC1 (ERCC1 产品)
- 别名
- COFS4 Protein, RAD10 Protein, UV20 Protein, Ercc-1 Protein, ercc1 Protein, T12H1.18 Protein, T12H1_18 Protein, UV REPAIR DEFICIENT 7 Protein, UVR7 Protein, ERCC excision repair 1, endonuclease non-catalytic subunit Protein, excision repair cross-complementing rodent repair deficiency, complementation group 1 Protein, DNA excision repair protein ERCC-1 Protein, nucleotide repair protein Protein, excision repair cross-complementation group 1 L homeolog Protein, excision repair cross-complementation group 1 Protein, ERCC1 Protein, Ercc1 Protein, CC1G_04546 Protein, CpipJ_CPIJ013903 Protein, PITG_13719 Protein, ercc1 Protein, ercc1.L Protein
- 背景
- ERCC1, also known as DNA excision repair protein ERCC-1, functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4). Recombinant human ERCC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- 分子量
- 32.5 kDa (297aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_001159521
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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