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TIMP2 Protein (His tag)

TIMP2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN1098377
发货至: 中国
  • 抗原 See all TIMP2 蛋白
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    蛋白类型
    Recombinant
    宿主
    • 10
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    资源
    • 19
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    大肠杆菌(E. Coli)
    标记
    This TIMP2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TIMP2 蛋白
  • 说明

    Synonyms: TIMP metallopeptidase inhibitor 2, CSC-21K, CSC21K

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    别名
    TIMP2 (TIMP2 产品)
    别名
    CSC-21K Protein, DDC8 Protein, timp2l Protein, zgc:65967 Protein, zgc:85799 Protein, D11Bwg1104e Protein, Timp-2 Protein, TIMP-2 Protein, etID32613.12 Protein, fa96h09 Protein, timp2 Protein, wu:fa96h09 Protein, zgc:136726 Protein, TIMP metallopeptidase inhibitor 2 Protein, TIMP metallopeptidase inhibitor 2b Protein, tissue inhibitor of metalloproteinase 2 Protein, TIMP metallopeptidase inhibitor 2a Protein, TIMP metallopeptidase inhibitor 2 L homeolog Protein, TIMP2 Protein, timp2b Protein, Timp2 Protein, timp2a Protein, timp2.L Protein
    背景
    TIMP2 is a natural inhibitor of the matrix metalloproteinases, a group of peptidases involved in of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, this protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular. Recombinant human TIMP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    26.1 kDa (232aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_003246
    途径
    cAMP Metabolic Process
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