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RGS1 Protein (His tag)

RGS1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098296
发货至: 中国
  • 抗原 See all RGS1 蛋白
    RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This RGS1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product RGS1 蛋白
  • 说明

    Synonyms: Regulator of G-protein signaling 1, 1R20, BL34, IER1, IR20

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
    别名
    RGS1 (RGS1 产品)
    别名
    1R20 Protein, BL34 Protein, IER1 Protein, IR20 Protein, RGS1 Protein, 1r20 Protein, bl34 Protein, ier1 Protein, ir20 Protein, regulator of G protein signaling 1 Protein, regulator of G-protein signaling 1 Protein, regulator of G-protein signaling 1 S homeolog Protein, Regulator of G-protein signaling 1 Protein, RGS1 Protein, Rgs1 Protein, rgs1.S Protein, rgs1 Protein
    背景
    RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Recombinant human RGS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    26 kDa (233aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_002913
    途径
    MAPK Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events
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