MCL-1 Protein (His tag)
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- 抗原 See all MCL-1 (MCL1) 蛋白
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MCL-1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MCL1 蛋白
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- 说明
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Synonyms: induced myeloid leukemia cell differentiation protein Mcl-1, BCL2L3, mcl1/EAT, myeloid cell leukemia sequence 1, Bcl-2-like protein 3
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 20% glycerol, 2 mM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
- 别名
- MCL1 (MCL1 产品)
- 别名
- BCL2L3 Protein, EAT Protein, MCL1-ES Protein, MCL1L Protein, MCL1S Protein, Mcl-1 Protein, TM Protein, bcl2-L-3 Protein, mcl1/EAT Protein, AW556805 Protein, mcl-1 Protein, fb72f02 Protein, wu:fb70a08 Protein, wu:fb72f02 Protein, zfMLP1 Protein, zfMcl-1a Protein, zgc:109835 Protein, zgc:109763 Protein, E3 Protein, E3-2 Protein, RNE3 Protein, RNU107 Protein, SNORA63A Protein, elF-4AII Protein, MCL1, BCL2 family apoptosis regulator Protein, myeloid cell leukemia sequence 1 Protein, MCL1, BCL2 family apoptosis regulator a Protein, MCL1, BCL2 family apoptosis regulator b Protein, small nucleolar RNA, H/ACA box 63 Protein, MCL1 Protein, Mcl1 Protein, mcl1a Protein, mcl1b Protein, SNORA63 Protein
- 背景
- MCL1, also known as BCL2L3, belongs to the Bcl-2 family. MCL1 is involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. Recombinant human MCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
- 分子量
- 37.2 kDa (347aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_068779
- 途径
- MAPK Pathway
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