UBE2G2 Protein (AA 1-165) (GST tag)
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- 抗原 See all UBE2G2 蛋白
- UBE2G2 (Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-165
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This UBE2G2 protein is labelled with GST tag.
- 原理
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 G2/UBE2G2/UBC7 (N-GST)
- 序列
- MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMAG TALKRLMAEY KQLTLNPPEG IVAGPMNEEN FFEWEALIMG PEDTCFEFGV FPAILSFPLD YPLSPPKMRF TCEMFHPNIY PDGRVCISIL HAPGDDPMGY ESSAERWSPV QSVEKILLSV VSMLAEPNDE SGANVDASKM WRDDREQFYK IAKQIVQKSL GL
- 产品特性
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Recombinant Human Ubiquitin-Conjugating Enzyme E2 G2/UBE2G2/UBC7 (N-GST)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product UBE2G2 蛋白
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Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) protein
UBE2G2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 1-165) protein (His tag)UBE2G2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 1-165) protein (GST tag)UBE2G2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 1-87) protein (GST tag)UBE2G2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 2-165) protein (His tag)Crystallography grade UBE2G2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (Transcript Variant 1) protein (His tag)UBE2G2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2G2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- UBE2G2 (Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2))
- 别名
- Ubiquitin-Conjugating Enzyme E2 G2/UBE2G2 (UBE2G2 产品)
- 别名
- UBC7 Protein, 1110003O05Rik Protein, D10Xrf369 Protein, Ubc7p Protein, wu:fu51c05 Protein, wu:fu56g11 Protein, zgc:112077 Protein, ubc7 Protein, ube2g1 Protein, ube2g2 Protein, wu:fi33c04 Protein, zgc:55974 Protein, ubiquitin conjugating enzyme E2 G2 Protein, ubiquitin-conjugating enzyme E2G 2 Protein, ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2 G2 Protein, Ubiquitin-conjugating enzyme E2 G2 Protein, ubiquitin conjugating enzyme E2 G2 L homeolog Protein, ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast) Protein, UBE2G2 Protein, Ube2g2 Protein, ube2g2 Protein, EDI_023910 Protein, CpipJ_CPIJ018658 Protein, Bm1_47630 Protein, ube2g2.L Protein, ube2g1a Protein
- 背景
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Recombinant Human Ubiquitin-Conjugating Enzyme E2 G2/UBE2G2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu165) of Human UBE2G2 fused with a GST tag at the N-terminus.
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60 % and 100 % sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s. - 分子量
- 45 kDa
- UniProt
- P60604
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