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TOLLIP Protein (AA 2-274) (His tag)

TOLLIP 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097679
发货至: 中国
  • 抗原 See all TOLLIP 蛋白
    TOLLIP (Toll Interacting Protein (TOLLIP))
    蛋白类型
    Recombinant
    产品特性
    AA 2-274
    宿主
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 6
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TOLLIP protein is labelled with His tag.
    原理
    Recombinant Human Toll-Interacting Protein/TOLLIP (C-6His)
    序列
    ATTVSTQRGP VYIGELPQDF LRITPTQQQR QVQLDAQAAQ QLQYGGAVGT VGRLNITVVQ AKLAKNYGMT RMDPYCRLRL GYAVYETPTA HNGAKNPRWN KVIHCTVPPG VDSFYLEIFD ERAFSMDDRI AWTHITIPES LRQGKVEDKW YSLSGRQGDD KEGMINLVMS YALLPAAMVM PPQPVVLMPT VYQQGVGYVP ITGMPAVCSP GMVPVALPPA AVNAQPRCSE EDLKAIQDMF PNMDQEVIRS VLEAQRGNKD AAINSLLQMG EEPVEHHHHH H
    产品特性
    Recombinant Human Toll-Interacting Protein is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Pro274) of Human TOLLIP fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TOLLIP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 mM EDTA, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    TOLLIP (Toll Interacting Protein (TOLLIP))
    别名
    Tollip (TOLLIP 产品)
    别名
    IL-1RAcPIP Protein, 4930403G24Rik Protein, 4931428G15Rik Protein, fk22a02 Protein, im:7145391 Protein, wu:fk22a02 Protein, zgc:76985 Protein, TOLLIP Protein, GB17961 Protein, tollip Protein, tollip1 Protein, tollipa Protein, TOLIP Protein, toll interacting protein Protein, toll-interacting protein Protein, toll-interacting protein-like Protein, toll interacting protein L homeolog Protein, toll interacting protein S homeolog Protein, Toll-interleukine I receptor interacting protein I Protein, TOLLIP Protein, Tollip Protein, tollip Protein, LOC552034 Protein, LOC100169858 Protein, tollip.L Protein, tollip.S Protein, LOC100136122 Protein
    Sub Type
    Fusionprotein
    背景
    Toll-Interacting Protein (TOLLIP) is a member of the tollip family. TOLLIP localizes to the cytoplasm. It contains one C2 domain and one CUE domain. TOLLIP is an inhibitory adaptor protein for Toll-like receptors (TLR). The Toll-like receptors pathway is a part of the immune system that recognize structurally conserved molecular patterns of microbial pathogens, resulting in an inflammatory immune response. TOLLIP constitutes a complex with Tom1 to regulate endosomal transferring of ubiquitinated proteins. TOLLIP can negative regulate Toll-like receptors signaling, which may limit the production of proinflammatory mediators during the process of inflammation and infection.
    Alternative Names: Toll-Interacting Protein, TOLLIP
    分子量
    31.3 kDa
    UniProt
    Q9H0E2
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