TOLLIP Protein (His tag)
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- 抗原 See all TOLLIP 蛋白
- TOLLIP (Toll Interacting Protein (TOLLIP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TOLLIP protein is labelled with His tag.
- 原理
- Recombinant Human TOLLIP Protein (His Tag)
- 序列
- Ala2-Pro274
- 产品特性
- Recombinant Human Toll-Interacting Protein is produced by our E.coli expression system and the target gene encoding Ala2-Pro274 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TOLLIP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 mM EDTA, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TOLLIP (Toll Interacting Protein (TOLLIP))
- 别名
- TOLLIP (TOLLIP 产品)
- 别名
- IL-1RAcPIP Protein, 4930403G24Rik Protein, 4931428G15Rik Protein, fk22a02 Protein, im:7145391 Protein, wu:fk22a02 Protein, zgc:76985 Protein, TOLLIP Protein, GB17961 Protein, tollip Protein, tollip1 Protein, tollipa Protein, TOLIP Protein, toll interacting protein Protein, toll-interacting protein Protein, toll-interacting protein-like Protein, toll interacting protein L homeolog Protein, toll interacting protein S homeolog Protein, Toll-interleukine I receptor interacting protein I Protein, TOLLIP Protein, Tollip Protein, tollip Protein, LOC552034 Protein, LOC100169858 Protein, tollip.L Protein, tollip.S Protein, LOC100136122 Protein
- 背景
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Background: Toll-Interacting Protein (TOLLIP) is a member of the tollip family. TOLLIP localizes to the cytoplasm. It contains one C2 domain and one CUE domain. TOLLIP is an inhibitory adaptor protein for Toll-like receptors (TLR). The Toll-like receptors pathway is a part of the immune system that recognize structurally conserved molecular patterns of microbial pathogens, resulting in an inflammatory immune response. TOLLIP constitutes a complex with Tom1 to regulate endosomal transferring of ubiquitinated proteins. TOLLIP can negative regulate Toll-like receptors signaling, which may limit the production of proinflammatory mediators during the process of inflammation and infection.
Synonym: Toll-Interacting Protein, TOLLIP
- 分子量
- 31.3 kDa
- UniProt
- Q9H0E2
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