TIE1 Protein (AA 22-760) (His tag)
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- 抗原 See all TIE1 蛋白
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-760
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宿主
- 人
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资源
- 人细胞
- 标记
- This TIE1 protein is labelled with His tag.
- 原理
- Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)
- 序列
- AVDLTLLANL RLTDPQRFFL TCVSGEAGAG RGSDAWGPPL LLEKDDRIVR TPPGPPLRLA RNGSHQVTLR GFSKPSDLVG VFSCVGGAGA RRTRVIYVHN SPGAHLLPDK VTHTVNKGDT AVLSARVHKE KQTDVIWKSN GSYFYTLDWH EAQDGRFLLQ LPNVQPPSSG IYSATYLEAS PLGSAFFRLI VRGCGAGRWG PGCTKECPGC LHGGVCHDHD GECVCPPGFT GTRCEQACRE GRFGQSCQEQ CPGISGCRGL TFCLPDPYGC SCGSGWRGSQ CQEACAPGHF GADCRLQCQC QNGGTCDRFS GCVCPSGWHG VHCEKSDRIP QILNMASELE FNLETMPRIN CAAAGNPFPV RGSIELRKPD GTVLLSTKAI VEPEKTTAEF EVPRLVLADS GFWECRVSTS GGQDSRRFKV NVKVPPVPLA APRLLTKQSR QLVVSPLVSF SGDGPISTVR LHYRPQDSTM DWSTIVVDPS ENVTLMNLRP KTGYSVRVQL SRPGEGGEGA WGPPTLMTTD CPEPLLQPWL EGWHVEGTDR LRVSWSLPLV PGPLVGDGFL LRLWDGTRGQ ERRENVSSPQ ARTALLTGLT PGTHYQLDVQ LYHCTLLGPA SPPAHVLLPP SGPPAPRHLH AQALSDSEIQ LTWKHPEALP GPISKYVVEV QVAGGAGDPL WIDVDRPEET STIIRGLNAS TRYLFRMRAS IQGLGDWSNT VEESTLGNGL QAEGPVQESR AAEEGLDQQV DHHHHHH
- 产品特性
- Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 produced by transfected human cells is a secreted protein with Human TIE1 (A22-Q760) fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TIE1 蛋白
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tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 785-1138) protein (His tag)
Crystallography grade TIE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 781-1134) protein (His tag)Crystallography grade TIE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 22-759) protein (His tag)Crystallography grade TIE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 23-755) protein (His tag)Crystallography grade TIE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 22-1138) protein (rho-1D4 tag)Crystallography grade TIE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 23-1134) protein (rho-1D4 tag)Crystallography grade TIE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
- 别名
- tie-1 (TIE1 产品)
- 别名
- JTK14 Protein, TIE Protein, D430008P04Rik Protein, tie-1 Protein, tyrosine kinase with immunoglobulin like and EGF like domains 1 Protein, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 Protein, tyrosine-protein kinase receptor Tie-1 Protein, endothelium-specific receptor tyrosine kinase 1 Protein, TIE1 Protein, Tie1 Protein, CpipJ_CPIJ018933 Protein, tie1 Protein
- Sub Type
- Fusionprotein
- 背景
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TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2)], but no ligand was found for TIE-1.
Alternative Names: Tyrosine-Protein Kinase Receptor Tie-1, TIE1, TIE - 分子量
- 81 kDa
- UniProt
- P35590
- 途径
- RTK signaling
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