我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Sonic Hedgehog Protein (SHH) (AA 24-197)

This Recombinant Sonic Hedgehog protein is expressed in 大肠杆菌（E. Coli）.

产品编号 ABIN1097559

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Sonic Hedgehog Protein (SHH) (AA 24-197) (ABIN1097559)

抗原

See all Sonic Hedgehog (SHH) 蛋白

Sonic Hedgehog (SHH)

蛋白类型

Recombinant

宿主

人

资源

大肠杆菌（E. Coli）

纯度

> 95 % as determined by reducing SDS-PAGE.

Discover our top product SHH 蛋白

产品特性

AA 24-197

原理

Recombinant Human Sonic Hedgehog/SHH

序列

MCGPGRGFGK RRHPKKLTPL AYKQFIPNVA EKTLGASGRY EGKISRNSER FKELTPNYNP DIIFKDEENT GADRLMTQRC KDKLNALAIS VMNQWPGVKL RVTEGWDEDG HHSEESLHYE GRAVDITTSD RDRSKYGMLA RLAVEAGFDW VYYESKAHIH CSVKAENSVA AKSGG

产品特性

Recombinant Human Sonic Hedgehog/SHH is produced with our E. coli expression system. The target protein is expressed with sequence (Cys24-Gly197) of Human SHH.

过滤

0.2 μm filtered

内毒素水平

Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
想要此Protein的其他选项吗？

!

探索我们的预定义定制蛋白和定制蛋白服务！

您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案

Sonic Hedgehog (SHH) (AA 25-198), (Cys25IleIle-Mutant) (Active) protein
SHH 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active

Sonic Hedgehog (SHH) (AA 24-197), (Cys24IleIle-Mutant) (Active) protein
SHH 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active

Sonic Hedgehog (SHH) protein (His tag)
SHH 宿主: 小鼠宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.

Sonic Hedgehog (SHH) (Active) protein
SHH 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE Active

Sonic Hedgehog (SHH) (AA 181-280) protein (GST tag)
SHH 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

Sonic Hedgehog (SHH) protein (His tag)
SHH 宿主: 人宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.

Sonic Hedgehog (SHH) (Active) protein (His tag)
SHH 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active

Sonic Hedgehog (SHH) (AA 25-198) protein (His tag)
SHH 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS

Sonic Hedgehog (SHH) protein
SHH 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS

Sonic Hedgehog (SHH) (AA 24-197) protein (His tag)
SHH 宿主: 人宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.

限制

仅限研究用
状态

Lyophilized

溶解方式

It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

缓冲液

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 1 mM DTT, pH 7.5.

储存液

Dithiothreitol (DTT)

注意事项

This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

储存条件

4 °C/-20 °C/-80 °C

储存方法

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

有效期

3 months
抗原

Sonic Hedgehog (SHH)

别名

Sonic Hedgehog/SHH

背景

Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
Alternative Names: Sonic Hedgehog Protein, SHH, HHG-1

分子量

19.69 kDa

UniProt

Q15465

途径

Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development