RAGE Protein (AA 23-344) (His tag)
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- 抗原 See all RAGE (AGER) 蛋白
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-344
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宿主
- 人
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资源
- 人细胞
- 标记
- This RAGE protein is labelled with His tag.
- 原理
- Recombinant Human AGER/RAGE (C-6His)
- 序列
- AQNITARIGE PLVLKCKGAP KKPPQRLEWK LNTGRTEAWK VLSPQGGGPW DSVARVLPNG SLFLPAVGIQ DEGIFRCQAM NRNGKETKSN YRVRVYQIPG KPEIVDSASE LTAGVPNKVG TCVSEGSYPA GTLSWHLDGK PLVPNEKGVS VKEQTRRHPE TGLFTLQSEL MVTPARGGDP RPTFSCSFSP GLPRHRALRT APIQPRVWEP VPLEEVQLVV EPEGGAVAPG GTVTLTCEVP AQPSPQIHWM KDGVPLPLPP SPVLILPEIG PQDQGTYSCV ATHSSHGPQE SRAVSISIIE PGEEGPTAGS VGGSGLGTLA LAVDHHHHHH
- 产品特性
- Recombinant Human Advanced Glycosylation End Product-Specific Receptor/AGER produced by transfected human cells is a secreted protein with sequence(Ala23-Ala344) of Human AGER fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product AGER 蛋白
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Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-340) protein (His tag)
AGER 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-344) protein (His tag)AGER 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-342) protein (His tag)AGER 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-342) protein (His-DYKDDDDK-Strep II Tag)AGER 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 362-404) protein (His-IF2DI Tag)AGER 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 134-231) protein (GST tag)AGER 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) protein (GST tag)AGER 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 87-197) protein (GST tag)AGER 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-237) protein (GST tag)AGER 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Advanced Glycosylation End Product-Specific Receptor (AGER) (Active) protein (His tag)AGER 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- 别名
- sRage (AGER 产品)
- 别名
- RAGE Protein, AGER Protein, advanced glycosylation end-product specific receptor Protein, advanced glycosylation end product-specific receptor Protein, MAPK/MAK/MRK overlapping kinase Protein, AGER Protein, Ager Protein, LOC719012 Protein
- Sub Type
- Fusionprotein
- 背景
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Advanced Glycosylation End Product-Specific Receptor (AGER) belongs to the immunoglobulin superfamily of cell surface molecules. It lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Besides AGEs, AGER is also able to bind other ligands which is thought to result in pro-inflammatory gene activation. It is known that AGER serve as a mediator of both acute and chronic vascular inflammation in certain conditions such as atherosclerosis and in particular as a complication of diabetes. Furthermore, it plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.
Alternative Names: Advanced Glycosylation End Product-Specific Receptor, Receptor for Advanced Glycosylation End Products, AGER, RAGE - 分子量
- 35.2 kDa
- UniProt
- Q15109
- 途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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