QPRT Protein (AA 1-297) (His tag)
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- 抗原 See all QPRT 蛋白
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-297
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This QPRT protein is labelled with His tag.
- 原理
- Recombinant Human Quinolinate Phosphoribosyltransferase/QPRTase (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MDAEGLALLL PPVTLAALVD SWLREDCPGL NYAALVSGAG PSQAALWAKS PGILAGQPFF DAIFTQLNCQ VSWFLPEGSK LVPVARVAEV RGPAHCLLLG ERVALNTLAR CSGIASAAAA AVEAARGAGW TGHVAGTRKT TPGFRLVEKY GLLVGGAASH RYDLGGLVMV KDNHVVAAGG VEKAVRAARQ AADFALKVEV ECSSLQEAVQ AAEAGADLVL LDNFKPEELH PTATVLKAQF PSVAVEASGG ITLDNLPQFC GPHIDVISMG MLTQAAPALD FSLKLFAKEV APVPKIH
- 产品特性
- Recombinant Human Quinolinate Phosphoribosyltransferase [Decarboxylating]/QPRT is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-His297) of Human QPRT fused with a His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product QPRT 蛋白
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Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (His tag)
QPRT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (GST tag)QPRT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) protein (GST tag)QPRT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (Strep Tag)Crystallography grade QPRT 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-299) protein (Strep Tag)Crystallography grade QPRT 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) protein (Myc-DYKDDDDK Tag)QPRT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0 .
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- 别名
- QAPRTase (QPRT 产品)
- 别名
- ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
- Sub Type
- Fusionprotein
- 背景
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Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
Alternative Names: Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating], Quinolinate Phosphoribosyltransferase [Decarboxylating], QAPRTase, QPRTase, QPRT - 分子量
- 33 kDa
- UniProt
- Q15274
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