SHP1 Protein (AA 243-541) (His tag)
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- 抗原 See all SHP1 (PTPN6) 蛋白
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 243-541
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SHP1 protein is labelled with His tag.
- 原理
- Recombinant Human Protein-Tyrosine Phosphatase 1C/PTP1C (C-6His)
- 序列
- MKAGFWEEFE SLQKQEVKNL HQRLEGQRPE NKGKNRYKNI LPFDHSRVIL QGRDSNIPGS DYINANYIKN QLLGPDENAK TYIASQGCLE ATVNDFWQMA WQENSRVIVM TTREVEKGRN KCVPYWPEVG MQRAYGPYSV TNCGEHDTTE YKLRTLQVSP LDNGDLIREI WHYQYLSWPD HGVPSEPGGV LSFLDQINQR QESLPHAGPI IVHCSAGIGR TGTIIVIDML MENISTKGLD CDIDIQKTIQ MVRAQRSGMV QTEAQYKFIY VAIAQFIETT KKKLEVLQSQ KGQESEYGNI LEHHHHHH
- 产品特性
- Recombinant Human Protein-Tyrosine Phosphatase 1C/PTP1C is produced with our E. coli expression system. The target protein is expressed with sequence (Lys243-Ile541) of Human PTP1C
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PTPN6 蛋白
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Protein-tyrosine Phosphatase 1C (PTPN6) (AA 5-163) protein (His-IF2DI Tag)
PTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Protein-tyrosine Phosphatase 1C (PTPN6) proteinPTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597) protein (GST tag)PTPN6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA, PAA
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 243-541) (Active) proteinPTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 207-597) (Active) protein (GST tag,His tag)PTPN6 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (Strep Tag)Crystallography grade PTPN6 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) protein (Strep Tag)Crystallography grade PTPN6 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Protein-tyrosine Phosphatase 1C (PTPN6) (Transcript Variant 1) protein (His tag)PTPN6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 25 mM TrisHCl, 2 mM ß-ME, 1 mM EDTA, 1 mM DTT, 20 % Glycerol, pH 7.5.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
- 别名
- Protein-Tyrosine Phosphatase 1C/PTP1C (PTPN6 产品)
- 别名
- HCPH Protein, HPTP1C Protein, PTP-1C Protein, SH-PTP1 Protein, SHP-1 Protein, SHP-1L Protein, SHP1 Protein, DRPLA Protein, Hcph Protein, Ptp1C Protein, me Protein, motheaten Protein, Ptph6 Protein, Shp-1 Protein, fj22f05 Protein, wu:fj22f05 Protein, zgc:55501 Protein, ptpn6 Protein, protein tyrosine phosphatase, non-receptor type 6 Protein, protein tyrosine phosphatase, non-receptor type 6 L homeolog Protein, PTPN6 Protein, Ptpn6 Protein, ptpn6 Protein, ptpn6.L Protein
- 背景
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Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors.
Alternative Names: Tyrosine-Protein Phosphatase Non-Receptor Type 6, Hematopoietic Cell Protein-Tyrosine Phosphatase, Protein-Tyrosine Phosphatase 1C, PTP-1C, Protein-Tyrosine Phosphatase SHP-1, SH-PTP1, PTPN6, HCP, PTP1C - 分子量
- 35.38 kDa
- UniProt
- P29350
- 途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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