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Oncomodulin Protein (OCM) (AA 2-109) (His tag)

OCM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097295
发货至: 中国
  • 抗原 See all Oncomodulin (OCM) 蛋白
    Oncomodulin (OCM)
    蛋白类型
    Recombinant
    产品特性
    AA 2-109
    宿主
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 14
    • 9
    大肠杆菌(E. Coli)
    标记
    This Oncomodulin protein is labelled with His tag.
    原理
    Recombinant Human Oncomodulin-1/OM (N-6His)
    序列
    MGSSHHHHHH SSGLVPRGSH MSITDVLSAD DIAAALQECR DPDTFEPQKF FQTSGLSKMS ANQVKDVFRF IDNDQSGYLD EEELKFFLQK FESGARELTE SETKSLMAAA DNDGDGKIGA EEFQEMVHS
    产品特性
    Recombinant Human Oncomodulin-1/OM is produced by our E. coli expression system. The target protein is expressed with sequence (Ser2-Ser109) of Human OCM fused with a His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product OCM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 7.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    Oncomodulin (OCM)
    别名
    Parvalbumin-beta (OCM 产品)
    别名
    OM Protein, Ocm Protein, oncmodulin Protein, OCM1 Protein, ONCM Protein, CBP-15 Protein, ocm1 Protein, oncm Protein, MGC189033 Protein, pvalb2 Protein, oncomodulin Protein, oncomodulin 2 Protein, Parvalbumin beta-like Protein, oncomodulin-1 Protein, oncomodulin L homeolog Protein, parvalbumin beta Protein, Ocm Protein, Ocm2 Protein, MGC53763 Protein, OCM Protein, LOC738473 Protein, ocm Protein, LOC100357024 Protein, ocm.L Protein, LOC100516001 Protein, LOC109097012 Protein, LOC102362774 Protein
    Sub Type
    Fusionprotein
    背景
    Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.
    Alternative Names: Oncomodulin-1, OM, Parvalbumin Beta, OCM, OCM1, OCMN
    分子量
    14.3 kDa
    UniProt
    P0CE72
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