Oncomodulin Protein (OCM) (His tag)
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Quick Overview for Oncomodulin Protein (OCM) (His tag) (ABIN7318847)
抗原
See all Oncomodulin (OCM) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Oncomodulin protein is labelled with His tag.
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原理
- Recombinant Human Oncomodulin-1/OCM Protein (His Tag)
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序列
- Met 1-Ser109
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产品特性
- Recombinant Human Oncomodulin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ser109 is expressed with a 6His tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Oncomodulin (OCM) (AA 2-109) protein (His-IF2DI Tag)
OCM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Oncomodulin (OCM) (AA 2-109) protein (His-IF2DI Tag)OCM 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Oncomodulin (OCM) (AA 1-113) protein (His tag)OCM 宿主: Gadus morhua subsp. callarias 宿主: 酵母菌 Recombinant > 90 % ELISA
Oncomodulin (OCM) (AA 26-220) protein (GST tag)OCM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
Oncomodulin (OCM) proteinOCM 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Oncomodulin (OCM) proteinOCM 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Oncomodulin (OCM)
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别名
- Oncomodulin-1/OCM
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背景
- OCM,OCM1,OCMN,OM,Oncomodulin-1,Parvalbumin Beta,Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.
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分子量
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Calculated MW: 14.3 kDa
Observed MW: 16 kDa
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基因ID
- 654231
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UniProt
- P0CE72
抗原
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