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Oncomodulin Protein (OCM) (His tag)

OCM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318847
发货至: 中国
  • 抗原 See all Oncomodulin (OCM) 蛋白
    Oncomodulin (OCM)
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 14
    • 8
    大肠杆菌(E. Coli)
    标记
    This Oncomodulin protein is labelled with His tag.
    原理
    Recombinant Human Oncomodulin-1/OCM Protein (His Tag)
    序列
    Met 1-Ser109
    产品特性
    Recombinant Human Oncomodulin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ser109 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product OCM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, pH 7.5.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Oncomodulin (OCM)
    别名
    Oncomodulin-1/OCM (OCM 产品)
    别名
    OM Protein, Ocm Protein, oncmodulin Protein, OCM1 Protein, ONCM Protein, CBP-15 Protein, ocm1 Protein, oncm Protein, MGC189033 Protein, pvalb2 Protein, oncomodulin Protein, oncomodulin 2 Protein, Parvalbumin beta-like Protein, oncomodulin-1 Protein, oncomodulin L homeolog Protein, parvalbumin beta Protein, Ocm Protein, Ocm2 Protein, MGC53763 Protein, OCM Protein, LOC738473 Protein, ocm Protein, LOC100357024 Protein, ocm.L Protein, LOC100516001 Protein, LOC109097012 Protein, LOC102362774 Protein
    背景

    Background: Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.

    Synonym: Oncomodulin-1, OM, Parvalbumin Beta, OCM, OCM1, OCMN

    分子量
    14.3 kDa
    UniProt
    P0CE72
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