LDLR Protein (AA 22-788) (His tag)
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- 抗原 See all LDLR 蛋白
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-788
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宿主
- 人
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资源
- 人细胞
- 标记
- This LDLR protein is labelled with His tag.
- 原理
- Recombinant Human Low-Density Lipoprotein Receptor/LDLR (C-6His)
- 序列
- AVGDRCERNE FQCQDGKCIS YKWVCDGSAE CQDGSDESQE TCLSVTCKSG DFSCGGRVNR CIPQFWRCDG QVDCDNGSDE QGCPPKTCSQ DEFRCHDGKC ISRQFVCDSD RDCLDGSDEA SCPVLTCGPA SFQCNSSTCI PQLWACDNDP DCEDGSDEWP QRCRGLYVFQ GDSSPCSAFE FHCLSGECIH SSWRCDGGPD CKDKSDEENC AVATCRPDEF QCSDGNCIHG SRQCDREYDC KDMSDEVGCV NVTLCEGPNK FKCHSGECIT LDKVCNMARD CRDWSDEPIK ECGTNECLDN NGGCSHVCND LKIGYECLCP DGFQLVAQRR CEDIDECQDP DTCSQLCVNL EGGYKCQCEE GFQLDPHTKA CKAVGSIAYL FFTNRHEVRK MTLDRSEYTS LIPNLRNVVA LDTEVASNRI YWSDLSQRMI CSTQLDRAHG VSSYDTVISR DIQAPDGLAV DWIHSNIYWT DSVLGTVSVA DTKGVKRKTL FRENGSKPRA IVVDPVHGFM YWTDWGTPAK IKKGGLNGVD IYSLVTENIQ WPNGITLDLL SGRLYWVDSK LHSISSIDVN GGNRKTILED EKRLAHPFSL AVFEDKVFWT DIINEAIFSA NRLTGSDVNL LAENLLSPED MVLFHNLTQP RGVNWCERTT LSNGGCQYLC LPAPQINPHS PKFTCACPDG MLLARDMRSC LTEAEAAVAT QETSTVRLKV SSTAVRTQHT TTRPVPDTSR LPGATPGLTT VEIVTMSHQA LGDVAGRGNE KKPSSVRLEN LYFQGHHHHH H
- 产品特性
- Recombinant Human Low-Density Lipoprotein Receptor/LDLR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala22-Arg788) of Human LDLR fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LDLR 蛋白
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Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His tag)
LDLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His-Avi Tag)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Low Density Lipoprotein Receptor (LDLR) (AA 105-205) protein (GST tag)LDLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His-Avi Tag,Biotin)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 455-607) protein (His-IF2DI Tag)LDLR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Low Density Lipoprotein Receptor (LDLR) (AA 1-860) protein (GST tag)LDLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (Active) protein (His tag)LDLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 别名
- LDL-receptor (LDLR 产品)
- 别名
- FH Protein, FHC Protein, LDLCQ2 Protein, Hlb301 Protein, LDLRA Protein, LDLA Protein, LDL receptor-2 Protein, fhc Protein, ldlcq2 Protein, ldlr Protein, ldlr2-a Protein, LDL receptor 1 Protein, ldlr-a Protein, ldlr-b Protein, low density lipoprotein receptor Protein, low density lipoprotein receptor a Protein, low density lipoprotein receptor S homeolog Protein, low density lipoprotein receptor L homeolog Protein, LDLR Protein, Ldlr Protein, ldlra Protein, ldlr.S Protein, ldlr.L Protein
- Sub Type
- Fusionprotein
- 背景
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Low-Density Lipoprotein Receptor (LDLR) is a transmembrane glycoprotein that plays a critical role in cholesterol homeostasis. LDLR mediates blood cholesterol level by interacting with lipoprotein particles like LDL and VLDL. The extracellular domain of LDLR contains LDL receptor type A (ligand-binding) modules (LA repeats), epidermal growth factor-like modules, and LY repeats containing the YWTD consensus motif that are important in binding and releasing of ApoB-100 and ApoE in lipoprotein particles. The C terminal domain of LDLR inside the cell is required for the receptor internalization. Loss of function mutations in the LDLR gene causes Familial Hypercholesterolemia (FH).
Alternative Names: Low-Density Lipoprotein Receptor, LDL Receptor, LDLR - 分子量
- 84.78 kDa
- UniProt
- P01130
- 途径
- Hepatitis C, Lipid Metabolism
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