IMPA2 Protein (AA 1-288) (His tag)
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- 抗原 See all IMPA2 蛋白
- IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-288
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IMPA2 protein is labelled with His tag.
- 原理
- Recombinant Human Inositol Monophosphatase 2/IMPase 2 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MKPSGEDQAA LAAGPWEECF QAAVQLALRA GQIIRKALTE EKRVSTKTSA ADLVTETDHL VEDLIISELR ERFPSHRFIA EEAAASGAKC VLTHSPTWII DPIDGTCNFV HRFPTVAVSI GFAVRQELEF GVIYHCTEER LYTGRRGRGA FCNGQRLRVS GETDLSKALV LTEIGPKRDP ATLKLFLSNM ERLLHAKAHG VRVIGSSTLA LCHLASGAAD AYYQFGLHCW DLAAATVIIR EAGGIVIDTS GGPLDLMACR VVAASTREMA MLIAQALQTI NYGRDDEK
- 产品特性
- Recombinant Human Inositol Monophosphatase 2/IMPase 2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys288) of Human IMPA2 fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IMPA2 蛋白
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Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-288) protein (His tag)
IMPA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) (AA 1-288) protein (GST tag)IMPA2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2) protein (Myc-DYKDDDDK Tag)IMPA2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 2 mM DTT, pH 8.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
- 别名
- Inositol Monophosphatase 2/IMPase 2 (IMPA2 产品)
- 别名
- zgc:110201 Protein, 2210415D20Rik Protein, AI326924 Protein, AW259601 Protein, inositol monophosphatase 2 Protein, inositol(myo)-1(or 4)-monophosphatase 2 Protein, inositol (myo)-1(or 4)-monophosphatase 2 Protein, IMPA2 Protein, impa2 Protein, MGYG_08537 Protein, Impa2 Protein
- Sub Type
- Fusionprotein
- 背景
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Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.
Alternative Names: Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P - 分子量
- 33.5 kDa
- UniProt
- O14732
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