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IMPA2 Protein (His tag)

IMPA2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318621
发货至: 中国
  • 抗原 See all IMPA2 蛋白
    IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This IMPA2 protein is labelled with His tag.
    原理
    Recombinant Human IMPA2/IMPase 2 Protein (His Tag)
    序列
    Met 1-Lys288
    产品特性
    Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IMPA2 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 2 mM DTT, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    IMPA2 (Inositol(myo)-1(or 4)-Monophosphatase 2 (IMPA2))
    别名
    IMPA2/IMPase 2 (IMPA2 产品)
    别名
    zgc:110201 Protein, 2210415D20Rik Protein, AI326924 Protein, AW259601 Protein, inositol monophosphatase 2 Protein, inositol(myo)-1(or 4)-monophosphatase 2 Protein, inositol (myo)-1(or 4)-monophosphatase 2 Protein, IMPA2 Protein, impa2 Protein, MGYG_08537 Protein, Impa2 Protein
    背景

    Background: Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

    Synonym: Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P

    分子量
    33.5 kDa
    UniProt
    O14732
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