GFRA1 Protein (AA 25-429) (His tag)
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- 抗原 See all GFRA1 蛋白
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-429
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宿主
- 人
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资源
- 人细胞
- 标记
- This GFRA1 protein is labelled with His tag.
- 原理
- Recombinant Human GDNF Family Receptor α-1/GFRA1 (C-6His)
- 序列
- DRLDCVKASD QCLKEQSCST KYRTLRQCVA GKETNFSLAS GLEAKDECRS AMEALKQKSL YNCRCKRGMK KEKNCLRIYW SMYQSLQGND LLEDSPYEPV NSRLSDIFRV VPFISVEHIP KGNNCLDAAK ACNLDDICKK YRSAYITPCT TSVSNDVCNR RKCHKALRQF FDKVPAKHSY GMLFCSCRDI ACTERRRQTI VPVCSYEERE KPNCLNLQDS CKTNYICRSR LADFFTNCQP ESRSVSSCLK ENYADCLLAY SGLIGTVMTP NYIDSSSLSV APWCDCSNSG NDLEECLKFL NFFKDNTCLK NAIQAFGNGS DVTVWQPAFP VQTTTATTTT ALRVKNKPLG PAGSENEIPT HVLPPCANLQ AQKLKSNVSG NTHLCISNGN YEKEGLGASS HITTKVDHHH HHH
- 产品特性
- Recombinant Human GDNF Family Receptor alpha-1/GFRA1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asp25-Lys429) of Human GFRA1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GFRA1 蛋白
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GDNF Family Receptor alpha 1 (GFRA1) (AA 25-424) protein (His tag)
GFRA1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
GDNF Family Receptor alpha 1 (GFRA1) (AA 267-360) protein (GST tag)GFRA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
GDNF Family Receptor alpha 1 (GFRA1) (AA 1-460) protein (GST tag)GFRA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (His tag)GFRA1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (His tag)GFRA1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (Active) protein (Fc Tag)GFRA1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
GDNF Family Receptor alpha 1 (GFRA1) (AA 25-429) protein (His tag)Crystallography grade GFRA1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
GDNF Family Receptor alpha 1 (GFRA1) (AA 25-430) protein (His tag)Crystallography grade GFRA1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- 别名
- gfr-alpha-1 (GFRA1 产品)
- 别名
- gdnfr Protein, ret1l Protein, retl1 Protein, trnr1 Protein, gdnfra Protein, MGC122616 Protein, gfr-alpha-1 Protein, GDNFR Protein, GDNFRA Protein, GFR-ALPHA-1 Protein, RET1L Protein, RETL1 Protein, TRNR1 Protein, GDNFRALPHA Protein, GFRA1 Protein, AU042498 Protein, gfralpha1a Protein, zgc:110129 Protein, GDNF family receptor alpha 1 Protein, glial cell line derived neurotrophic factor family receptor alpha 1 Protein, gdnf family receptor alpha 1a Protein, gfra1 Protein, GFRA1 Protein, Gfra1 Protein, gfra1a Protein
- Sub Type
- Fusionprotein
- 背景
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Glial Cell Line-Derived Neurotrophic Factor Family Receptor alpha-1 (GDNFRalpha1) is a glycosylphosphatidylinositol (GPI) linked cell surface protein belonging to GDNF-family receptor alpha subtype which consists of at least four members. GFRalpha1and GFRalpha2 are the cognate co-receptor for the neurotrophic factor neurturin mediating the NRTN-induced autophosphorylation and activation of the RET tyrosine kinase receptor. Soluble GFRalphas released enzymatically from the cell surface by phosphatidylinositol phospholipase C, as well as recombinantly produced soluble GFRalpha1, can also bind with high affinity to GDNF and trigger the activation of Ret tyrosine kinase. Human GFRalpha1 shares 93% amino acid identity with mouse GFRalpha1.The expression of the various GFRalphas are differentially regulated in the central and peripheral nervous system, suggesting complementary roles for the GFRalphas in mediating the activities of the GDNF family of neurotrophic factors.
Alternative Names: GDNF Family Receptor Alpha-1, GDNF Receptor Alpha-1, GDNFR-Alpha-1, GFR-Alpha-1, RET Ligand 1, TGF-Beta-Related Neurotrophic Factor Receptor 1, GFRA1, GDNFRA, RETL1, TRNR1 - 分子量
- 46.28 kDa
- UniProt
- P56159
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